Sarah Jones smiles for the camera. (Photos courtesy of Sarah Jones) This is Sarah Jones’ story: I thought on the day of my EGPA diagnosis — fully, eosinophilic granulomatosis with polyangiitis — that I was finally going to get on top of it and move on. Nothing could…
Living with EGPA disease is one big game of whack-a-mole
Argenx has decided not to go ahead with its development plans for efgartigimod as a potential treatment for ANCA-associated vasculitis (AAV) after the therapy failed to show beneficial effects in late-stage clinical trials of two other autoimmune diseases. Efgartigimod is approved in the U.S. in two formulations for…
Karna Karlsrud, left, poses for a photo with her daughter, Clea, who has vasculitis. (Photos courtesy of Karna Karlsrud) This is Karna Karlsrud’s story: When I adopted my beautiful daughter, Clea, 23 years ago, the social worker told me in many conversations that fantasy is worse than reality, so…
A Phase 1 clinical trial evaluating the safety and preliminary efficacy of Sana Biotechnology’s candidate CAR T-cell therapy SC291 in adults with ANCA-associated vasculitis (AAV) and other autoimmune diseases has started enrollment. The study, GLEAM (NCT06294236), is recruiting up to 36 patients ranging in age from 18…
Kathy Olevsky prepares to record a Vasculitis Foundation medical webinar in her office. (Photos courtesy of Kathy Olevsky) This is Kathy Olevsky’s story: In late 2008, I was diagnosed with microscopic polyangiitis or MPA. It plunged me into a 21-day hospital stay, including time in intensive care, filled…
Rituximab is superior to other immunosuppressive treatments at preventing post-surgery relapse in granulomatosis with polyangiitis (GPA) patients undergoing surgery to address subglottic stenosis, a common complication that causes airway narrowing. That’s according to a study that analyzed data from 25 GPA patients who were followed for more than…
Ioana Miclea has eosinophilic granulomatosis with polyangiitis. (Photos courtesy of Ioana Miclea) This is Ioana Miclea’s story. So, picture this: I’m Ioana, your quintessential 20-something girl, living it up with nights out, camping escapades, and a newfound love for festivals. And I’m jamming out to some meme song I…
Amgen is planning to launch a Phase 3 clinical trial testing Tavneos (avacopan) — its approved therapy for adults with ANCA-associated vasculitis (AAV) — in combination with a standard regimen of rituximab or cyclophosphamide in children and adolescents with active AAV. That’s according to a company press release…
Janice Barnett poses with a textile piece in the making. (Photos courtesy of Janice Barnett) This is Janice Barnett’s story: My diagnosis of eosinophilic granulomatosis with polyangiitis, formerly known as Churg-Strauss syndrome, in December 2021 plunged me into a state of utter disbelief. I was fit and…
Rachel Young learns to walk again in 2022. (Photos courtesy of Rachel Young) This is Rachel Young’s story: Young hikes in 2023. If I had ever heard the term “vasculitis” before my diagnosis three years ago (ANCA vasculitis with kidney involvement), it wasn’t something that held…
Recent Posts
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- Half of adults with AAV have interstitial lung disease at diagnosis, study finds
- Let’s do away with pity parties and start practicing self-compassion