This Year, I’m Finding Balance and Appreciating the Quiet

AAV Patients Vary on Preference for Plasma Exchange

Nearly one-third of adults with ANCA-associated vasculitis (AAV) would choose plasma exchange regardless of varying risks of kidney failure and severe infection, according to an international study. One-fifth of patients would make that choice only in high-risk scenarios and one-sixth would reject that treatment in all scenarios, however.

Protein Levels in Blood May Mark AAV Years Before Symptoms Do

The blood levels of several immune-related proteins are significantly altered in people with ANCA-associated vasculitis (AAV) up to five years before they develop symptoms when compared with matched healthy people, a study showed. Changes in these protein levels were found to be involved in inflammatory and metabolic pathways, and…

Rituximab Found Better for GPA Remission Than Cyclophosphamide

Rituximab is superior to cyclophosphamide at inducing disease remission after six months in people with granulomatosis with polyangiitis (GPA) — a type of ANCA-associated vasculitis (AAV) — according to a study in France. Similar findings were found for subgroups of GPA patients, such as those newly diagnosed with the disease…

Understanding Body Image and Acceptance With Vasculitis

Body image involves more than vanity. Though we often think of cosmetics and fitness as superficial, the reality is that they help us feel good about ourselves. We want to appeal to a mate, impress friends, and come off as professional to work colleagues. But everything about the physical body…

Top 10 ANCA-Associated Vasculitis Stories of 2022

Over the past year, ANCA Vasculitis News has brought you coverage of the latest developments in research related to ANCA-associated vasculitis (AAV). We look forward to continuing to bring you news about advances in research and treatment in the new year. Here we have compiled a list of the top…

Cyclophosphamide Plus Rituximab Prevents AAV Relapses: Study

Adding a low dose of cyclophosphamide to rituximab for remission induction was safe and more effective at preventing relapses in the first two years in people with severe ANCA-associated vasculitis (AAV) than rituximab alone, a new study shows. No significant benefit was observed in the combination treatment after five years.