A protein known as NGAL — fully, neutrophil gelatinase-associated lipocalin — appears to be a marker of disease activity and kidney damage severity in people with ANCA-associated vasculitis (AAV) who have kidney inflammation, according to new research by scientists in China. The team found that “in active AAV, [blood]…
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Two Phase 1/2 clinical trials testing NKX019 — Nkarta’s cell therapy candidate — are now enrolling participants to test a second, higher dose in people with ANCA-associated vasculitis (AAV) and other autoimmune conditions. The Ntrust-2 study (NCT06733935) is enrolling up to 144 people with AAV, idiopathic inflammatory…
Most people who test positive for ANCAs — the self-reactive antibodies that drive most ANCA-associated vasculitis (AAV) cases — have pauci-immune glomerulonephritis (GN), a type of inflammation of the kidneys’ filtering units, a study found. A high number of blood-clotting-inducing platelets, high blood levels of the inflammatory marker…
Becoming educated and informed about ANCA vasculitis is a good first step. Here you’ll find general information such as the diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your ANCA vasculitis journey.
There is no cure for ANCA vasculitis yet, but here you can find more information about current approved treatments, as well as experimental treatments that are in the pipeline.
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