Posts by: Marisa Wexler, MS

Marisa Wexler, MS

Marisa holds an MS in Cellular and Molecular Pathology from the University of Pittsburgh, where she studied novel genetic drivers of ovarian cancer. She specializes in cancer biology, immunology, and genetics. Marisa began working with BioNews in 2018, and has written about science and health for SelfHacked and the Genetics Society of America. She also writes/composes musicals and coaches the University of Pittsburgh fencing club.

September 10, 2020September 10, 2020

AAV Carries High Healthcare Costs, Italian Study Finds

News

ANCA-associated vasculitis (AAV) carries high healthcare costs for therapies and hospitalizations to treat the disease itself and related infections, a study in Italy has found. The study, “Healthcare and ... Read more

September 3, 2020September 3, 2020

Muscle Biopsies Could Be Useful in AAV Diagnosis, Study Asserts

News

Muscle biopsies could be used to diagnose ANCA-associated vasculitis (AAV), a new study indicates. The finding suggests that such biopsies are most informative in females or in people with ... Read more

August 17, 2020August 17, 2020

Extracellular Vesicles of Neutrophils May Be Blood Biomarkers for AAV

News

Extracellular vesicles, or the tiny membrane-bound particles that are released from cells, could be used as a blood biomarker of disease activity in people with ANCA-associated vasculitis (AAV), a new ... Read more

August 13, 2020August 13, 2020

Complement System Overactive in AAV Patients With Active Disease, Study Finds

News

The complement system, a part of the immune system, is overactive in people with active ANCA-associated vasculitis (AAV), but achieving remission appears to lower most of its components to ... Read more

July 30, 2020July 30, 2020

ANCA Status, B-cell Levels After Rituximab Treatment Predict Relapses, Study Finds

News

The presence of detectable ANCA antibodies and B-cells after initial treatment with rituximab — used to induce remission in people with ANCA-associated vasculitis (AAV) — predicts a greater risk ... Read more

July 27, 2020July 27, 2020

Complement System Activation May Be Linked to Kidney Disease in AAV Patients

News

The complement system, a component of the immune system, is overactive in people with necrotizing glomerulonephritis, or inflammation in the tiny blood vessels of the kidneys, caused by ANCA-associated ... Read more

July 23, 2020July 23, 2020

Fingolimod May Have Potential as AAV Treatment, Rat Study Indicates

News

Fingolimod (FTY720), a medication used to treat multiple sclerosis, also appears to ease many of the symptoms of ANCA-associated vasculitis (AAV), a new study in rats suggests. The study, ... Read more

June 29, 2020June 29, 2020

Eligibility, Outcome Measures Need Uniformity Across AAV Clinical Trials, Review Says

News

Clinical trials testing new treatments for people with ANCA-associated vasculitis (AAV) need more uniformity in the patients they recruit and in the outcome measures used for efficacy assessments, a ... Read more

June 15, 2020June 15, 2020

Kidney Involvement at AAV Diagnosis Predicts Major Renal Relapses, Study Finds

News

People with ANCA-associated vasculitis (AAV) who have kidney involvement when they are diagnosed are more likely to experience major kidney relapses later, a new study shows. The study also ... Read more

June 11, 2020June 11, 2020

Guidelines Given for Rituximab as Maintenance Therapy in 3 AAV Subtypes

News

Guidelines for using rituximab as a maintenance therapy in adults with ANCA-associated vasculitis (AAV) were recently published that, in addition to helping physicians with treatment approaches, highlight areas where ... Read more

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