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Low dose of corticosteroids as good as high dose for AAV: Study

A low dose of intravenous or into-the-vein methylprednisolone, a corticosteroid, is as safe and effective as a high dose at preserving kidney function and extending survival in people with severe ANCA-associated vasculitis (AAV), a U.K. study found. Given that corticosteroids, a standard AAV treatment, are associated with significant…

Long-term Nucala or benralizumab effective in EGPA real-world study

Two years of treatment with Nucala (mepolizumab) safely and effectively reduces signs and symptoms of hard-to-treat eosinophilic granulomatosis with polyangiitis (EGPA), the rarest form of ANCA-associated vasculitis. That’s according to a real-world study in Italy that also found similar outcomes with benralizumab, a therapy that works similarly to…