People with ANCA-associated vasculitis (AAV) who develop bronchiectasis — a chronic lung condition marked by permanent widening of certain parts of the airways — may face a higher risk of serious infections and death, according to a new study. The researchers found that bronchiectasis in individuals with granulomatosis with polyangiitis…
Kidney tissue patterns may influence treatment response in AAV
Before ANCA-associated vasculitis (AAV), I never gave breathing a second thought. It was automatic, like blinking or walking across a room. Then came a day when I walked from my bedroom to the kitchen and couldn’t breathe. There were actually many days like this, but I will never forget…
A risk score that combines blood tests and kidney biopsy findings performed among the strongest tools for predicting kidney failure in people with ANCA-associated vasculitis (AAV), a small study suggests. The analysis also showed that all three risk scoring systems evaluated remained linked to the risk of kidney failure…
At diagnosis, half of adults with ANCA-associated vasculitis (AAV) already have signs of interstitial lung disease (ILD), a condition marked by inflammation and progressive scarring of lung tissue, according to a new single-center study in Italy. Evidence of lung disease was particularly prevalent among those with microscopic polyangiitis (MPA),…
If I could erase one term from the vocabulary of people affected by chronic or rare diseases like ANCA vasculitis, it would be “pity party,” closely followed by “sorry for myself.” Those words are cruel. Not dramatic. Not motivating. Cruel. When we say them to ourselves, we’re not being…
ANCA-associated vasculitis (AAV) patients with antibodies targeting the myeloperoxidase (MPO) protein have higher levels of immune-activating pieces of the C3 protein in their urine, and these are closely associated with measures of disease severity, a small study showed. “These fragments may serve as sensitive, [noninvasive] biomarkers for [kidney] immune…
Lung complications are common among adults with ANCA-associated vasculitis (AAV), affecting four in five individuals throughout their disease course, with some developing lasting damage, a study found. According to the new analysis of more than 1,000 patients in the U.S. and Canada, patterns of lung involvement differed between those…
Some of the best things I’ve learned about living with ANCA vasculitis didn’t come from a journal article, a conference slide deck, or even a clinic visit. They came from you. From conversations. From comments. From private, patient-focused Facebook groups — messages that started with, “Does anyone else …”…
Adults with ANCA-associated vasculitis (AAV) who test positive for antibodies against the myeloperoxidase (MPO) protein may face cardiovascular events sooner than those with antibodies against the proteinase-3 (PR3) protein, according to a new study. The French study analyzed data from 402 adults with AAV. While the overall proportion of…
Recent Posts
- Kidney tissue patterns may influence treatment response in AAV
- Chronic lung condition doubles infection risk in AAV patients: Study
- I often can’t breathe automatically due to lung issues and AAV
- New kidney risk score shows strong predictive power in AAV study
- Half of adults with AAV have interstitial lung disease at diagnosis, study finds