Posts by: Steve Bryson PhD

Steve Bryson PhD

Steve holds a PhD in Biochemistry from the Faculty of Medicine at the University of Toronto, Canada. He worked as a medical scientist for 18 years, within both industry and academia, where his research focused on the discovery of new medicines to treat inflammatory disorders and infectious diseases. Steve recently stepped away from the lab and into science communications, where he’s helping make medical science information more accessible for everyone.

November 18, 2020November 18, 2020

Monitoring Autoantibodies in AAV Helps Predict Remission, Relapse, Study Finds

News

Changes in autoantibodies that target the protein PR3 in people with ANCA-associated vasculitis (AAV) may help predict sustained remission following treatment, and eventual disease relapses, a study found. The ... Read more

October 12, 2020October 12, 2020

Heat Shock Proteins in Kidneys Linked to Poorer Outcomes in AAV Patients

News

A group of proteins that modulate immune responses, called heat shock proteins (HSPs), are significantly elevated in the kidneys of people with ANCA-associated vasculitis (AAV), and their levels are ... Read more

July 2, 2020July 2, 2020

AAV Rare in COPD Patients With AAT Deficiency, Study Finds

News

Low levels of the protein alpha-1-antitrypsin (AAT) do not appear to be enough to increase the risk of ANCA-associated vasculitis (AAV) in people with chronic obstructive pulmonary disease (COPD) ... Read more

June 22, 2020June 22, 2020

Depression More Common in AAV, Linked to Pain, Lower Quality of Life

News

Depression is more common in people with primary systemic vasculitides, including in those with ANCA-associated vasculitis (AAV), than in healthy people, a review study has found. Depression in vasculitis patients ... Read more

February 24, 2020February 24, 2020

Study Recommends AAV Renal Risk Score to Predict Serious Kidney Disease in Patients

News

A combination of both blood tests and biopsy (tissue) analysis was better at predicting end-stage renal disease in people with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) compared to tissue analysis ... Read more

February 17, 2020February 17, 2020

Kidney Infections Can Mimic AAV Symptoms, Case Study Finds

News

Blood vessels in the kidneys that swell due to an infection can mimic ANCA-associated vasculitis (AAV), making diagnosis and treatment of these two conditions challenging, a case study shows. ... Read more

January 29, 2020January 29, 2020

Non-Specific GPA-AAV Symptoms Misdiagnosed as Pneumonia, Case Study Reports

News

An elderly woman was diagnosed with the granulomatosis with polyangiiti (GPA) subtype of ANCA-associated vasculitis (AAV) after being misdiagnosed with pneumonia, illustrating the challenges in diagnosing this condition, according to ... Read more

January 22, 2020January 22, 2020

Study Identifies Risk Factors for Higher Cardiovascular Disease Rates in AAV Patients With GPA and EGPA

News

A family history of cardiovascular disease and higher vasculitis disease activity are risk factors for fatal and non-fatal cardiac disease in patients with anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis, a ... Read more

January 8, 2020January 8, 2020

Elevated Microparticle Levels in AAV Patients Mark Higher Risk of Blood Clots, Study Suggests

News

People with anti‑neutrophil cytoplasmic antibody (ANCA)‑associated vasculitis (AAV) who have high levels of cellular microparticles in their blood may be at higher risk for venous thromboembolism (VTE), a life-threatening ... Read more

November 4, 2019November 4, 2019

Fewer Relapses, Lower Steroid Doses After Dialysis in Japanese AAV Patients, Study Reports

News

Dialysis for Japanese patients with kidney disease triggered by ANCA-associated vasculitis led to fewer life-threatening relapses and reduced doses of immunosuppressive steroids, a long-term study suggests. The study, “Long‑term follow‑up ... Read more