ChemoCentryx Amends Approval Application for Avacopan

ChemoCentryx has filed an amendment to its application seeking approval of avacopan, an investigational therapy for the treatment of ANCA-associated vasculitis (AAV). The filing addresses the issues raised by an advisory committee of independent medical experts during a recent meeting with the U.S. Food and Drug…

I’m in the gym, on minute 17 of the stair-stepper machine, exhausted and desperately watching the timer count up to 20. That’s today’s goal: nonstop stepping on levels five and six for 20 minutes. This session is bookended by a 10-minute treadmill warmup and cooldown to get my heart rate…

At its first virtual investor event, biotech company Centogene set a bold mission: to cure 100 rare diseases within the next decade. A leader in the field of genetic diagnostics, Centogene used the June 22 event to present its strategic priorities, outlining its plans to speed the discovery…

When the weather is nice, I tend to forget I’m sick. The sun is shining, the yard is green and inviting, and I don’t even have to put on shoes to enjoy it all. (In fact, according to the grounding technique, it might be healthier not to!) There are…

Using lower doses of prednisolone in combination with Rituxan (rituximab) resulted in similar rates of remission and fewer adverse events than Rituxan plus higher doses of the glucocorticoid in treating ANCA-associated vasculitis (AAV). Those were the findings of a Phase 4 clinical trial in Japan that examined the effects…

Creating ways to speed the process of getting an accurate diagnosis would help the health outcomes of patients with ANCA-associated vasculitis and other types of vasculitis, a study says. Delays in obtaining an accurate diagnosis are linked to unemployment, the need to travel long distances to a medical center,…

Summer mornings in my house are deliciously slow. Around 8 a.m., the dogs know our first task is to go outside and tend to the plants. I fill a watering can and make the rounds: vegetables, herb garden, succulents on the porch, and tea plants on the patio. The better…

To help patient advocacy leaders and their partners better understand how global health statistics codes — known as ICD codes — are assigned, updated, and revised in the U.S. health information system, the EveryLife Foundation for Rare Diseases is presenting a first-of-its-kind resource guide. The foundation created the…

Those who wish to gain practical tools for living optimally with rare diseases are encouraged to attend the annual Living Rare Living Stronger Patient and Family Forum, hosted by the National Organization for Rare Disorders (NORD) and set this year for June 26-27. The conference brings together patients,…

Treatment with ChemoCentryx’s investigational therapy avacopan can improve kidney function in people with ANCA-associated vasculitis to a greater extent than steroids, especially among individuals with advanced kidney disease, clinical trial data show. The data were presented at the annual meeting of the European Renal Association –…