Posts by: Iqra Mumal

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The protein myeloperoxidase (MPO) may increase the activation of neutrophils — key immune cells in ANCA-associated vasculitis — and heighten vascular injury in patients, a new study shows. The study, “Myeloperoxidase influences ... Read more

May 21, 2018

Interstitial Lung Disease May Develop in Patients with Any AAV Subtype, Study Suggests

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Interstitial lung disease — a group of conditions characterized by scarring of the lungs — may develop in patients with all three subtypes of ANCA-associated vasculitis (AAV), a retrospective ... Read more

May 15, 2018

Cytokine Levels Can Distinguish Autoantibody Types in AAV Patients, Study Shows

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The levels of certain immune molecules called cytokines in the blood are better at identifying the types of specific autoantibodies present in ANCA-associated vasculitis (AAV) patients than at determining ... Read more

May 10, 2018

Kidney Function in Patients with Severe Renal Disease May Be Helped by Longer Immunosuppressive Use, Study Suggests

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Prolonging immunosuppressive use may help patients with severe ANCA-associated glomerulonephritis —inflammation of the kidney — who still need dialysis after a standard three-month treatment, a study suggests. The study, ... Read more

April 19, 2018April 19, 2018

Low Immune Protein Levels Predict Worse ANCA-associated Vasculitis Survival, Study Finds

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Low levels of two immune system proteins increase the risk that a person who has just been diagnosed with ANCA-associated vasculitis will die or have a serious kidney problem, a ... Read more

April 17, 2018

Avacopan Safer, More Effective than Standard Therapy in AAV Patients, Phase 2 Trials Show

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Patients with ANCA-associated vasculitis (AAV) have fewer adverse events and better quality of life when treated with avacopan over standard therapy, results from two Phase 2 clinical trials show. ... Read more

April 12, 2018

Faulty Immune System Component in AAV Leads to Neutrophil Activation, Kidney Damage, Study Shows

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A faulty immune system component in patients with active ANCA-associated vasculitis (AAV) is not equipped to stop ANCA-induced neutrophil activation, leading to kidney damage, a Chinese study shows. The component ... Read more

March 13, 2018

GPA Patients with Ear, Nose, and Throat Symptoms Have Fewer Kidney Problems, Better Survival Rates, Study Finds

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Ear, nose, and throat symptoms in patients with granulomatosis with polyangiitis (GPA) are associated with better overall survival and fewer kidney problems, according to researchers. The study, “Ear, nose ... Read more

February 20, 2018February 20, 2018

AAV Patients in Japan on Low Daily Prednisone Doses as Maintenance Therapy Seen as More Likely to Relapse

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Low daily doses of oral prednisone — 2.5 mg/day or less — during long-term remission maintenance therapy was associated with a higher rate of relapse in patients with antineutrophil cytoplasmic ... Read more

February 15, 2018February 15, 2018

Shorter Glucocorticoid Treatment Combined with Rituxan Could Benefit Some AAV Patients, Study Says

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A shorter glucocorticoid treatment course, given in combination with Rituxan (rituximab), may be beneficial for some patients with ANCA-associated vasculitis, a study shows. The study, “Reducing glucocorticoid duration in ... Read more

Posts by: Iqra Mumal

Iqra Mumal

Protein Myeloperoxidase May Lead to Worse Outcomes in AAV Patients

Interstitial Lung Disease May Develop in Patients with Any AAV Subtype, Study Suggests

Cytokine Levels Can Distinguish Autoantibody Types in AAV Patients, Study Shows

Kidney Function in Patients with Severe Renal Disease May Be Helped by Longer Immunosuppressive Use, Study Suggests

Low Immune Protein Levels Predict Worse ANCA-associated Vasculitis Survival, Study Finds

Avacopan Safer, More Effective than Standard Therapy in AAV Patients, Phase 2 Trials Show

Faulty Immune System Component in AAV Leads to Neutrophil Activation, Kidney Damage, Study Shows

GPA Patients with Ear, Nose, and Throat Symptoms Have Fewer Kidney Problems, Better Survival Rates, Study Finds

AAV Patients in Japan on Low Daily Prednisone Doses as Maintenance Therapy Seen as More Likely to Relapse

Shorter Glucocorticoid Treatment Combined with Rituxan Could Benefit Some AAV Patients, Study Says

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