Author Archives: Ana Pena, PhD

ANCA Autoantibodies Produced in Healthy People, Study Shows

Healthy individuals also produce a type of self-reactive antibodies — termed IgM ANCA — present in people with ANCA-associated vasculitis (AAV), a study has found. While low, the levels in healthy people are comparable with those in AAV patients whose disease is less active. The antibodies’ role is still…

Distinct ANCA Autoantibodies Predict Different Organ Involvement, Outcomes in AAV, Study Shows

Classifying the specificity of ANCA autoantibodies may complement the currently used clinical classification system when predicting the course of disease and prognosis in ANCA-associated vasculitis (AAV) patients with renal involvement, according to Spanish researchers. Indeed, ANCA specificity was seen to be better at predicting relapse than clinical classification.