News

Lupus Nephritis Patients with ANCA Antibodies Have More Aggressive Kidney Disease, Case Report Suggests

Lupus nephritis patients positive for ANCA antibodies show mixed symptoms of systemic lupus erythematosus and ANCA-associated vasculitis, culminating in aggressive kidney disease that does not respond well to remission-inducing therapies, a case report suggests. The study, “Rapid progression to end‐stage renal disease in a young female with mixed…

Nonprofit Group Works to Raise Rare Disease Awareness in India

With an estimated 1.37 billion inhabitants, India will likely surpass China in five years as the world’s most populous country. That also means it will have more rare-disease patients than any nation. It already has more than twice as many as the 28-member European Union. Harsha K. Rajasimha, a genomics…

Rituxan Deemed Safe, Effective for Refractory or Relapsing GPA Patients

Genentech‘s Rituxan (rituximab) is safe and effective to induce and maintain remission in patients with refractory or relapsing granulomatous manifestations (inflamed tissue) due to granulomatosis with polyangiitis (GPA), according to a new study. The findings were presented at the recent 19th International Vasculitis and ANCA Workshop in Philadelphia, Pennsylvania,…

Heart Valve Damage Might Be Cause of Breathing Difficulties in ANCA-Associated Vasculitis, Case Report Says

While breathing difficulties in ANCA-associated vasculitis patients are often a symptom of worsening vasculitis in their lungs, doctors should also consider cardiac valve involvement — or damage to heart valves — as a possible cause, a case report suggests. The study, “Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis Causes Aortic…