José Lopes, PhD, managing science editor —

José holds a PhD in neuroscience from the University of Porto, Portugal. After postdocs at Weill Connell Medicine and Western University, where he studied the processes driving hypertension and Alzheimer’s disease, he moved on in 2016 to a career in science writing and communication. José is the author of several peer-reviewed papers and a book chapter and has presented his research in numerous international meetings.

Articles by José Lopes

New Mouse Model of AAV May Reveal Role of Specific DNA Regions

A new mouse model of ANCA-associated vasculitis (AAV) shows glomerulonephritis, lung vasculitis, and MPO-ANCA autoantibodies, among other alterations seen in patients with the disease. These mice may help determine genetic factors in AAV, the researchers said. The study, “Vasculitis and Glomerulonephritis in a Newly Established…

Lipid Level Increases Could Indicate Cardiovascular Risk in ANCA Vasculitis Subsets, Study Reports

Patients with ANCA-associated vasculitis (AAV) experience significant increases in serum lipid levels during remission induction, particularly those who are newly diagnosed or have anti-PR3 antibodies, according to new research. The findings also indicated that disease phase and antibody type are associated with differential levels of inflammation and could…

Antiphospholipid Antibodies Linked to Risk of Blood Clots in AAV Patients

Patients with ANCA-associated vasculitis (AAV) who have persistent antiphospholipid antibodies (APLAs) at diagnosis are at a greater risk of developing blood clots, with consequent obstruction of the blood flow, according to new research. The study, “Persistent antiphospholipid antibodies are associated with thrombotic events in ANCA-associated vasculitis: A retrospective…

Dividing AAV According to Antibodies Provides No Further Benefit for Prognosis, Study Reports

Dividing ANCA-associated vasculitis (AAV) into subgroups defined by type of antibodies does not provide additional value for clinical prognosis, according to recent research. The study, “Clinical impact of subgrouping ANCA-associated vasculitis according to antibody specificity beyond the clinicopathological classification,” appeared in the journal Rheumatology. Different…