Posts by: Alejandra Viviescas, PhD.

Alejandra Viviescas, PhD.

May 2, 2019

Tumors in Thymus May Cause ANCA-associated Vasculitis, Case Report Suggests

News

Tumors in the thymus can lead to a malfunction of the immune system, and cause the appearance of ANCA-associated vasculitis, a case report suggests. However, the association is rare, and more ... Read more

April 30, 2019April 30, 2019

Lupus Nephritis Patients with ANCA Antibodies Have More Aggressive Kidney Disease, Case Report Suggests

News

Lupus nephritis patients positive for ANCA antibodies show mixed symptoms of systemic lupus erythematosus and ANCA-associated vasculitis, culminating in aggressive kidney disease that does not respond well to remission-inducing therapies, a case ... Read more

April 23, 2019

Expanded ANCA Testing May Improve AAV Diagnosis, Classification, Study Says

News

A new test that recognizes anti-neutrophil cytoplasmic autoantibodies (ANCAs) targeting proteins other than myeloperoxidase (MPO) and proteinase-3 (PR-3) could improve the diagnosis and classification of ANCA-associated vasculitis, a study suggests. ... Read more

April 16, 2019

Heart Valve Damage Might Be Cause of Breathing Difficulties in ANCA-Associated Vasculitis, Case Report Says

News

While breathing difficulties in ANCA-associated vasculitis patients are often a symptom of worsening vasculitis in their lungs, doctors should also consider cardiac valve involvement — or damage to heart valves — ... Read more

April 15, 2019April 15, 2019

Donor Antibodies Given Intravenously May Treat ANCA Vasculitis, Early Study Reports

News

Intravenous immunoglobulin therapy – which essentially consists on pooled antibodies from a thousand or more blood donors – could be a promising way of treating MPO-positive ANCA-associated vasculitis patients, ... Read more

April 2, 2019

PR3-ANCA Vasculitis May Cause Internal Organ Damage Due to Inadequate Blood Supply, Case Report Suggests

News

Patients with ANCA-associated vasculitis producing PR3-ANCA antibodies may have inadequate blood delivery to internal organs, such as the kidneys and spleen, leading to organ malfunction and pain, a case ... Read more

March 5, 2019

Low-dose Radiotherapy Could Treat Cancer Caused by GPA Lesions, Case Report Suggests

News

Tumors caused by granulomatosis with polyangiitis (GPA)-related lesions appear to be especially sensitive to radiation and can be treated effectively with low-dose radiotherapy, a case report suggests. The study, “Radiotherapy ... Read more

February 26, 2019

Study: IV Methylprednisolone Doesn’t Benefit, May Harm AAV Patients

News

Adding intravenous methylprednisolone pulses to standard treatment for inducing remission in severe cases of ANCA-associated vasculitis does not confer clinical benefits and increases the risk of infection and diabetes, a study suggests. ... Read more

February 21, 2019

New Test May Help Determine Disease Activity in GPA Patients, Study Reports

News

A new test measuring the relative abundance of immunoglobulin G4 (IgG4) RNA could be an indicator of granulomatosis with polyangiitis (GPA) activity and distinguish active disease from remission, a study suggests. ... Read more

February 14, 2019

Reduced Muscle Strength Leads to Poor Quality of Life in ANCA Vasculitis Patients, Study Says

News

Long-term disease and treatment-related damage reduce the muscle strength and physical capacity of people with ANCA-associated vasculitis. The resulting reduction in physical activity diminishes the quality of life, a ... Read more

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