Author Archives: Marisa Wexler MS

Study Identifies AAV-associated Genetic Variants in Chinese Population

Variants in immune-related genes may make certain people more or less susceptible to anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), a new study suggests. The study, “Risk HLA class II alleles and amino acid residues in myeloperoxidase–ANCA-associated vasculitis,” was published in the journal Kidney International.  The fact…

AAV Neutrophils Show Increased Activation of the Alternative Complement System, Study Finds

Neutrophils from patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are better at activating the alternative complement system than neutrophils from healthy people, a study has found. This research emphasizes the role of complement in AAV disease development, and suggests the therapeutic potential of its inhibition. The study, titled…

Antibody Fragment May Be Used to Treat ANCA Vasculitis, Study Reports

A piece of an antibody targeting a protein involved in cholesterol transport and metabolism might be an effective treatment for anti-neutrophil cytoplasmic autoantibodies (ANCA) vasculitis, a study suggests. The study, “Efficacy of a recombinant single-chain fragment variable region, VasSF, as a new drug for vasculitis,” was published in …