Little UV Exposure, Low Vitamin D Levels Tied to Relapse Risk in AAV

Limited exposure to ultraviolet (UV) light and related drops in vitamin D levels — particularly over the winter months — may be linked to a greater risk of relapses among people with ANCA-associated vasculitis (AAV) in Ireland and the U.K., a data study found. But vitamin D status and…

People with granulomatosis with polyangiitis (GPA) may, in rare cases, develop dilated cardiomyopathy, a condition that causes the heart’s chambers to enlarge and become thinner, making it harder for it to pump blood effectively to the rest of the body, a recent case report shows. This case highlights the…

As a kid, my mom would make me write a thank-you note to anyone who gave me a gift. It was an attempt to teach me gratitude, but I hated writing in cursive, which made my hand cramp up. I thought the process horribly old-fashioned and tedious, but I did…

Undetectable blood levels of ANCAs within six months of remission induction treatment were associated with a lower risk of relapses over the next five years in people with ANCA-associated vasculitis (AAV), a study showed. The presence or absence of disease-causing antibodies did not seem to impact the risk of…

ANCA-associated vasculitis (AAV) emerged as a side effect of levamisole given for years to treat a 15-year-old boy with idiopathic nephrotic syndrome, according to a case report. “By reporting this case, we want to raise awareness among clinicians regarding a rare complication of treatment with Levamisole that is often…

In the world of chronic illness, everything seems to be viewed in terms of time. There’s no room for impatience when your body struggles with a long-term disease. If you make a change to your regimen for the good, such as an updated diet or exercise routine, it will…

A 65-year-old man developed granulomatosis with polyangiitis (GPA), a type of anti-neutrophilic cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), after receiving a stem cell transplant for another autoimmune condition, according to a case report. “[Our] case report suggests that [AAV] may develop in the setting of stem cell transplantation and must…

People with eosinophilic granulomatosis with polyangiitis (EGPA) are more likely to report a greater range of symptoms than their doctors, a study that drew on patient- and physician-reported databases found, while showing similarities on other points, like relapse frequency. Given the importance of the patient perspective in both research and…

A man with granulomatosis with polyangiitis — a type of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) — and abnormally raised urine protein levels, a sign of kidney disease, has been described in a recent case report. Notably, urine protein levels usually are not significantly elevated in people with granulomatosis…

A subtype of antibody-producing B-cells was significantly higher in the bloodstream of ANCA-associated vasculitis (AAV) patients with active kidney involvement compared with those who were in remission and healthy individuals. These findings may help monitor disease progression, as well as provide insights into AAV development, the researchers noted. The…