News

Cyclophosphamide and Rituxan May Safely Treat AAV Patients During Pregnancy, Study Finds

Standard therapies used to ANCA-associated vasculitis (AAV), like cyclophosphamide or Rituxan (rituximab), appear to be of benefit in patients who are pregnant, a literature review suggests. The study, “Successful treatment outcomes in pregnant patients with ANCA‐associated vasculitides: A systematic review of literature,” was published in the International Journal…

Rare SLE-AAV Overlap Syndrome May Cause Stroke, Case Report Shows

While rare, ANCA-associated vasculitis (AAV) may overlap with systemic lupus erythematosus (SLE) — the most common form of lupus — and manifest as an hemorrhagic stroke caused by a weakened blood vessel in the brain, a case study shows. The study, “Systemic lupus erythematosus and antineutrophilic cytoplasmic…

Woman with Double-Positive Disease Treated with Plasma Exchange Combo, Case Study Shows

A woman in Japan diagnosed with both ANCA-associated vasculitis and anti-glomerular basement membrane (GBM) disease — an extremely rare medical condition known as double-positive disease — was successfully treated with plasma exchange and cyclophosphamide,  according to a case report. The case study, “Successful treatment of steroid-refractory double-positive ANCA and…

New Classification System Enables Prediction of Kidney Function and Survival in ANCA Glomerulonephritis Patients

A new classification system of types of glomerular lesions in the kidney enables better prediction of renal function and survival in patients with ANCA-associated glomerulonephritis, according to a nationwide study in Japan. The research, “Histopathological classification of anti-neutrophil cytoplasmic antibody-associated glomerulonephritis in a nationwide Japanese prospective…