News

Neurological Symptoms in AAV Patients Do Not Impact Likely Long-term Survival, Study Reports

Almost half of patients diagnosed with ANCA-associated vasculitis (AAV) showed neurological symptoms in a single-site, retrospective study from India. But while nervous system involvement appears to be more common than thought, it does not affect long-term survival, its researchers said. The study, “Neurological Manifestations Do not Affect Cumulative Survival…

Lung Ultrasound Accurately Detects Lesions in AAV, Study Shows

Lesions in the lungs caused by ANCA-associated vasculitis (AAV) are variable among patients, but lung ultrasound appears to be as good as computed tomography (CT) scans at detecting them, a study found. The study, “Utility of lung ultrasound in ANCA-associated vasculitis with lung involvement,” was published…

New Mouse Model of AAV May Reveal Role of Specific DNA Regions

A new mouse model of ANCA-associated vasculitis (AAV) shows glomerulonephritis, lung vasculitis, and MPO-ANCA autoantibodies, among other alterations seen in patients with the disease. These mice may help determine genetic factors in AAV, the researchers said. The study, “Vasculitis and Glomerulonephritis in a Newly Established…

Study Identifies AAV-associated Genetic Variants in Chinese Population

Variants in immune-related genes may make certain people more or less susceptible to anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), a new study suggests. The study, “Risk HLA class II alleles and amino acid residues in myeloperoxidase–ANCA-associated vasculitis,” was published in the journal Kidney International.  The fact…