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August 16, 2018

Case Report Describes Patient with Muscle Condition Who Developed Acute Kidney Disease Due to Overlapping Vasculitis

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Patients with dermatomyositis — a condition marked by muscle weakness and a distinctive skin rash — can develop acute kidney disease due to overlapping autoimmune diseases affecting the small vessels, ... Read more

August 13, 2018

Levels of Pro-inflammatory Molecule Can Predict Poor Outcomes in AAV, Study Finds

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Patients with ANCA-associated vasculitis (AAV) with elevated SDMA — a pro-inflammatory molecule — in their blood have a greater risk of kidney failure or death, according to researchers. Their research, “Higher ... Read more

August 7, 2018

Ratio Between 2 Types of Immune Cells Can Predict Risk of Relapse in ANCA Vasculitis Patients, Study Finds

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The ratio of neutrophils to lymphocytes — two types of immune cells — can be used to predict disease activity at diagnosis and risk of relapse in patients with ... Read more

August 6, 2018

While Uncommon, AAV Patients May Have Overlapping Autoimmune Disease, Study Suggests

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Roughly 1 in 10 patients with ANCA-associated vasculitis have another overlapping autoimmune disease, such as rheumatoid arthritis, lupus, or scleroderma, according to a study. Patients whose vasculitis is limited ... Read more

August 2, 2018

FDA Clears 2 PerkinElmer’s Assays to Help Diagnose ANCA Vasculitis

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The U.S Food and Drug Administration (FDA) cleared two assays to be used in the diagnosis of ANCA-associated vasculitis (AAV), according to PerkinElmer. Specifically, the FDA cleared the EUROPLUS ... Read more

July 31, 2018

Biopsy Combined with Other Tests Can Better Predict Kidney Survival, Study Finds

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Patients with ANCA-associated vasculitis (AAV) who have renal symptoms might benefit from a kidney biopsy along with measurements of ANCA antibodies and kidney function to predict their renal outcomes, a ... Read more

July 30, 2018

Renal Artery Rupture a Rare Complication of Microscopic Polyangiitis, Case Study Reports

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A case study from Japan found that patients with microscopic polyangiitis can, on rare occasions, develop aneurysms in their renal arteries, a complication that can lead to blood vessel rupture ... Read more

July 26, 2018

Aortic Aneurysm Occurred as Complication of Granulomatosis with Polyangiitis, Case Report Says

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Patients with granulomatosis with polyangiitis can rarely develop abdominal aortic aneurysm, a serious condition that can lead to blood vessel rupture and, in extreme circumstances, death. The case report ... Read more

July 23, 2018

Kidney Biopsies Help Predict End-Stage Disease in Older AAV Patients, Study Shows

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A kidney biopsy is valuable in establishing a diagnosis and prognosis for end-stage renal disease in older patients with ANCA-associated vasculitis who have kidney involvement, although they are not useful ... Read more

July 19, 2018

ANCA Vasculitis Can Develop in Scleroderma Patients in Rare Cases, Study Reports

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While rare, patients with scleroderma — a disease that causes skin hardening — can also develop ANCA-associated vasculitis, a case report shows. The study, “Perinuclear Antineutrophil Cytoplasmic Antibody Positive ... Read more

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