News

May 23, 2019

Urinary Gremlin Protein Levels a Potential Biomarker for ANCA-associated Renal Vasculitis, Study Finds

News

Levels of Gremlin — a protein that is overexpressed during kidney damage — in the urine may serve as a specific biomarker for ANCA-associated renal vasculitis, a study shows. ... Read more

May 21, 2019

First Patient Dosed in European Trial Testing IFX-1 Investigational Therapy, InflaRx Announces

News

The first patient has been dosed in InflaRx‘s ongoing European Phase 2 clinical trial testing the safety and efficacy of its IFX-1 investigational therapy for the treatment of ANCA-associated ... Read more

May 15, 2019

Rare Diseases Constitute a ‘Public Health Issue,’ NCATS Director Warns

News

With 250 rare diseases newly identified every year, scientists can barely keep up — even as the healthcare system fails millions of Americans whose rare diseases have already been ... Read more

May 14, 2019

ChemoCentryx on Track to Present Topline Data From its Ongoing ADVOCATE Phase 3 Trial on Avacopan

News

ChemoCentryx remains on track to report topline results later this year from its ongoing Phase 3 clinical trial assessing the safety and efficacy of oral avacopan (CCX168) in patients ... Read more

May 9, 2019

Cerebral Small Vessel Disease Can Be Detected Before Diagnosis of MPO-AAV, Study Suggests

News

In patients with MPO-positive ANCA-associated vasculitis, the excess inflammation causes cerebral small vessel disease even before the disease is diagnosed, and the risk for cerebral disease may remain high ... Read more

May 7, 2019

Stopping Immunosuppressants May Be OK for Some ANCA Vasculitis Patients, Study Suggests

News

A large proportion of patients with ANCA-associated vasculitis discontinue treatment while in remission, but they appear to have fewer relapses than those who never stopped treatment, a study has ... Read more

May 2, 2019

Tumors in Thymus May Cause ANCA-associated Vasculitis, Case Report Suggests

News

Tumors in the thymus can lead to a malfunction of the immune system, and cause the appearance of ANCA-associated vasculitis, a case report suggests. However, the association is rare, and more ... Read more

April 30, 2019April 30, 2019

Lupus Nephritis Patients with ANCA Antibodies Have More Aggressive Kidney Disease, Case Report Suggests

News

Lupus nephritis patients positive for ANCA antibodies show mixed symptoms of systemic lupus erythematosus and ANCA-associated vasculitis, culminating in aggressive kidney disease that does not respond well to remission-inducing therapies, a case ... Read more

April 25, 2019April 25, 2019

Nonprofit Group Works to Raise Rare Disease Awareness in India

News

With an estimated 1.37 billion inhabitants, India will likely surpass China in five years as the world’s most populous country. That also means it will have more rare-disease patients ... Read more

April 23, 2019

Expanded ANCA Testing May Improve AAV Diagnosis, Classification, Study Says

News

A new test that recognizes anti-neutrophil cytoplasmic autoantibodies (ANCAs) targeting proteins other than myeloperoxidase (MPO) and proteinase-3 (PR-3) could improve the diagnosis and classification of ANCA-associated vasculitis, a study suggests. ... Read more

Pin It on Pinterest