News

April 12, 2021April 12, 2021

FDA Committee Seeks Feedback on Avacopan Ahead of Public Meeting

News

A committee of the U.S. Food and Drug Administration (FDA) is holding a public meeting to discuss the potential approval of avacopan for the treatment of ANCA-associated vasculitis (AAV). During ... Read more

April 7, 2021April 7, 2021

Glucocorticoids, Respiratory Disease Raise Risk of Severe COVID-19 in AAV

News

In patients with systemic vasculitis like ANCA-associated vasculitis (AAV), glucocorticoid use and respiratory disease are linked with severe COVID-19 outcomes, a recent study reports. “Together with reports of other cohorts ... Read more

April 5, 2021April 5, 2021

Alliance Sets Treatment Plans by Consensus for Severe Pediatric AAV

News

The Childhood Arthritis and Rheumatology Research Alliance (CARRA) has established alternative consensus treatment plans for children and adolescents with severe ANCA-associated vasculitis (AAV). These plans, which compare two therapies for induction ... Read more

March 31, 2021April 1, 2021

Cost of Rare Diseases in US? Nearly $1 Trillion in 2019, EveryLife Foundation Finds

News, syndicated

As anyone affected by a rare disease knows, treating the illness while trying to go about everyday life is an expensive undertaking. But exactly how expensive — in terms of ... Read more

March 29, 2021March 29, 2021

Transplant Medication Found Comparable to Cyclophosphamide in Inducing Remission

News

People with ANCA-associated vasculitis (AAV) who receive mycophenolate mofetil (MMF) as a remission induction therapy have similar remission rates as those given cyclophosphamide (CYC), an analysis of eight published studies ... Read more

March 24, 2021March 24, 2021

Self-antibodies May Appear Years Before AAV Symptom Onset

News

The disease-causing autoantibodies are sometimes present long before the onset of ANCA-associated vasculitis (AAV) symptoms, with distinct disease features depending on their antibody type, a recent study finds. Overall, the ... Read more

March 22, 2021March 22, 2021

YKL-40 May Be Helpful Blood Biomarker of AAV Disease Activity

News

Levels of the chitinase-3-like 1 (YKL-40) protein in the blood may serve as a helpful biomarker of disease activity in people with ANCA-associated vasculitis (AAV), findings from a new study ... Read more

March 17, 2021March 17, 2021

Immune System’s Role AAV, Other Diseases Focus of Grant Award

News

Research into the potential interplay between different immune system components and coagulation in patients with ANCA-associated vasculitis (AAV), COVID-19 and systemic lupus erythematosus (SLE) has won a grant from the Academic Alliance ... Read more

March 15, 2021March 15, 2021

Timing of Rituximab Infusion May Affect COVID-19 Outcomes in AAV Patients

News

People with ANCA-associated vasculitis (AAV) who receive rituximab treatment may have a higher risk of severe COVID-19 outcomes and should therefore be considered vaccination priorities, a recent case report suggests. ... Read more

March 9, 2021March 8, 2021

Pink, Green, Blue and Purple Lights Illuminated World for Rare Disease Day

News, syndicated

Many diseases have their own awareness color — breast cancer is pink, muscular dystrophy is green, and AIDS is red, for example — but what’s the significance of pink, green, ... Read more