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October 18, 2018

Pregnant Women with ANCA-associated Vasculitis More Prone to Complications, Review Shows

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Women who develop ANCA-associated vasculitis while pregnant are more likely to suffer maternal and fetal complications, according to a systematic literature review. To ensure the best possible outcome, investigators ... Read more

October 16, 2018

Levamisole-laced Cocaine Led to ANCA Vasculitis and Kidney Damage, Case Report Recounts

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A patient in New York was diagnosed with ANCA-associated vasculitis and compromised kidney function caused by levamisole-adulterated cocaine, which scientists consider to be a rare occurrence. The study, “Unusual ... Read more

October 15, 2018

Tailored Rituxan Regimen for ANCA Vasculitis Patients as Effective, Possibly Safer than Fixed-schedule Treatment, Expert Says

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An individually tailored treatment with Rituxan (rituximab) is as effective as the standard fixed-schedule regimen in preventing relapses over 28 months in ANCA-associated vasculitis (AAV) patients in remission. The ... Read more

October 11, 2018

Cocaine Abuse Causes Symptoms that Mimic AAV, Complicating Diagnosis, Case Report Shows

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Inhaling cocaine regularly can cause tissue and blood changes that may mimic those found in patients with ANCA-associated vasculitis (AAV), a case report shows. These findings suggest that in ... Read more

October 10, 2018October 9, 2018

Advocacy Groups, Doctors Question Rising Prices of Rare Disease Treatments

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Half a year has gone by since disgraced pharma executive Martin Shkreli was sentenced to seven years in federal prison for securities and wire fraud while heading San Diego-based ... Read more

October 9, 2018

Minimal Glucocorticoid Regimen Shows Similar Efficacy, Fewer Adverse Events than Standard Treatments, Study Reports

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Patients with ANCA-associated vasculitis (AAV) who receive a minimal glucocorticoid treatment along with Rituxan (rituximab) and cyclophosphamide show similar improvement as those given standard glucocorticoid regimens, but have lower glucocorticoid-associated adverse events, ... Read more

October 8, 2018

Muscle Weakness a Rare Presenting Symptom of ANCA-associated Vasculitis, Case Report Shows

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Muscle weakness may, in rare cases, be a presenting symptom of ANCA-associated vasculitis, and a muscle biopsy should be considered in these cases to confirm a diagnosis, a case report ... Read more

October 2, 2018

Atypical ANCAs Do Not Contribute to Vessel Inflammation in Patients with Eye Disease, Study Suggests

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The presence of atypical ANCA antibodies in people with underlying eye inflammatory disease is not linked to severe vessel inflammation or worse outcomes, a small study reports. The study, ... Read more

October 1, 2018

Small-vessel Vasculitides Linked to Worse Prognosis During ICU Stays, Polish Study Finds

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Patients with small-vessel vasculitides, including ANCA-associated vasculitis, are more likely to need aggressive treatments or to die in the intensive care unit (ICU) than patients with other systemic autoimmune diseases, ... Read more

September 27, 2018September 28, 2018

Measuring ANCA Levels in Sputum May Improve EPGA Diagnosis, Management, Study Suggests

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Most patients with eosinophilic granulomatosis with polyangiitis (EGPA) test positive for anti-neutrophil cytoplasmic autoantibodies (ANCAs) in sputum samples, even if they show no signs of them in their blood, ... Read more

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