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August 22, 2019

Improved Classification Systems Needed for AAV, Study Shows

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The autoimmune condition ANCA-associated vasculitis (AAV) needs improved classification systems that can better predict disease outcomes, a Spanish study says. Disease management should be based more on individual patient ... Read more

August 20, 2019

Intravenous Immunoglobulin Quickly Lowers Disease Activity in AAV Patients, Review Study Finds

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Intravenous immunoglobulin (IVIG) therapy leads to a fast and significant reduction in disease activity, as well as in the levels of inflammatory biomarkers, in people with ANCA-associated vasculitis (AAV), ... Read more

August 20, 2019August 19, 2019

Nebraska’s Neena Nizar Seeks Cure for Jansen’s, One of World’s Rarest Diseases

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Imagine living your whole life with a painful disease so rare that only 25 others worldwide have what you have. And that you’re one of just six such people ... Read more

August 19, 2019

Immune Cell Profile Classification Useful for Prognosis, Treatment of AAV, Study Finds

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Dividing people with active ANCA-associated vasculitis (AAV) into different subgroups may be useful for determining prognosis and selecting each person’s best course of treatment, researchers say. The classification method ... Read more

August 13, 2019

ANCA Autoantibodies Produced in Healthy People, Study Shows

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Healthy individuals also produce a type of self-reactive antibodies — termed IgM ANCA — present in people with ANCA-associated vasculitis (AAV), a study has found. While low, the levels ... Read more

August 12, 2019

AAV Involving Kidneys May Not Always Start in Glomeruli, Case Report Suggests

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ANCA-associated vasculitis (AAV) can cause kidney damage without affecting the glomeruli, the filtering unit of the kidneys, a case report suggests. Doctors should consider this possibility to avoid a ... Read more

August 8, 2019

Study Identifies Factors for Renal Recovery for AAV Patients on Dialysis for Kidney Damage

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Researchers say an important clinical assessment is determining whether ANCA-associated vasculitis patients who need dialysis at disease onset, due to severe kidney damage, can become dialysis independent. A study ... Read more

August 7, 2019

Development of Oral Candidiasis Predicts Severe Infections in AAV Patients Receiving Immunosuppressants, Study Shows

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ANCA-associated vasculitis patients who develop oral candidiasis during treatment with immunosuppressants have a significantly greater risk of severe infections compared to patients who never develop oral candidiasis, a study shows. ... Read more

August 5, 2019

Treating ANCA Vasculitis in Cancer Patients Best Approach, Case Study Suggests

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When autoimmune diseases such as ANCA-associated vasculitis are found at the same time as cancer, properly diagnosing and treating them alongside the cancer is crucial to ensuring best outcomes for ... Read more

August 2, 2019August 1, 2019

Oklahoma Ranks Lowest on Programs Key to Rare Diseases on NORD’s 2019 State Report Card

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Oklahoma suffers more tornadoes than any other state, has the highest per-capita rate of women in U.S. prisons, ranks second in the number of teen births per 100,000 teenage ... Read more

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