Author Archives: Iqra Mumal, MSc

Aortic Aneurysm Occurred as Complication of Granulomatosis with Polyangiitis, Case Report Says

Patients with granulomatosis with polyangiitis can rarely develop abdominal aortic aneurysm, a serious condition that can lead to blood vessel rupture and, in extreme circumstances, death. The case report with that finding, “Aortic Aneurysm as a Complication of Granulomatosis with Polyangiitis Successfully Treated with Prednisolone and Cyclophosphamide: A Case…

GPA Often Affects Eye, Requiring Care from Ophthalmologist, Study Suggests

Granulomatosis with polyangiitis (GPA) patients often experience eye involvement, suggesting an ophthalmologist is necessary for proper disease management and better outcomes, according to Egyptian researchers. Their study, “Relationship of ocular presentation in granulomatosis with polyangiitis to autoantibodies and disease activity,” was published in the journal Zeitschrift für…

Protein Myeloperoxidase May Lead to Worse Outcomes in AAV Patients

The protein myeloperoxidase (MPO) may increase the activation of neutrophils — key immune cells in ANCA-associated vasculitis — and heighten vascular injury in patients, a new study shows. The study, “Myeloperoxidase influences the complement regulatory activity of complement factor H,” was published in the journal Rheumatology. ANCA-associated vasculitis (AAV)…

Kidney Function in Patients with Severe Renal Disease May Be Helped by Longer Immunosuppressive Use, Study Suggests

Prolonging immunosuppressive use may help patients with severe ANCA-associated glomerulonephritis —inflammation of the kidney — who still need dialysis after a standard three-month treatment, a study suggests. The study, “Late restoration of renal function in patients with severe ANCA-associated glomerulonephritis who were dialysis-dependent at presentation,” was published…