Interstitial pneumonia may trigger the production of anti-neutrophil cytoplasmic antibodies (ANCA) and lead to a kind of vasculitis called microscopic polyangiitis, a case report shows. The finding suggests that interstitial pulmonary fibrosis may be a cause, rather than a consequence, of ANCA-associated vasculitis. The study, “Idiopathic Interstitial Pneumonia…
News
Treatment with immunosuppressants does not improve kidney function, but is associated with reduced risk of vasculitis relapse in a rare subset of patients with ANCA vasculitis (AAV), a new study reports. The research, “Patient Outcomes in Renal-Limited Antineutrophil Cytoplasmic Antibody Vasculitis With Inactive Histology,” was published…
Mexican researchers reported for the first time a patient with granulomatosis with polyangiitis (GPA) who experienced extensive, widespread gastrointestinal symptoms as the main manifestation of relapsing disease. The case was reported in the study, “Extensive Gastrointestinal Manifestations as the Main Relapsing Disease in Granulomatosis with Polyangiitis,” published…
Immunosuppressive Treatment of ANCA Vasculitis May Increase Patients’ Risk of Late-onset Pneumonia
Patients with ANCA-associated vasculitis using an immunosuppressive therapy may be at risk of late-onset pneumonia caused by opportunistic Pneumocystis jirovecii infection, a new study suggests. The study, “Late-onset Pneumocystis jirovecii pneumonia (PJP) in patients with ANCA-associated vasculitis,” was published in the journal Clinical Rheumatology. ANCA-associated vasculitis, or AAV, is characterized…
Microscopic polyangiitis with kidney manifestations, a subtype of ANCA-associated vasculitis, can develop in women after a pregnancy, a case report from Japan suggests. The study, “Microscopic polyangiitis necrotizing glomerulonephritis associated with pregnancy: case with a 20-year clinical course and review of the literature,” appeared in the journal…
Ultrasounds May Help Predict Artery Damage, Risk of Heart Problems in GPA Patients, Study Shows
A noninvasive and simple ultrasound test might be a new tool to help predict artery damage and increased risk of cardiovascular events in ANCA-associated vasculitis patients with granulomatosis with polyangiitis (GPA), according to researchers. Their study, “Endothelial dysfunction…
Researchers reported the case of a patient who developed suspected ANCA-associated vasculitis (AAV) in the ear followed by hearing loss after taking propylthiouracil, a thyroid medication for Graves’ disease. While the medicine has been widely linked with AAV in other studies, its ability to cause otitis and hearing loss is…
Men with ANCA-associated vasculitis (AAV) presenting kidney inflammation are more likely than women to progress into end-stage renal disease, according to Norwegian researchers. Their study, “Exploring sex-specific differences in the presentation and outcomes of ANCA-associated vasculitis: a nationwide registry-based cohort study,” was published in the journal…
Tapazole (methimazole), a thyroid medication used to treat Graves’ disease, may in rare cases cause ANCA-associated vasculitis (AAV), a new patient study suggests. While the link between thyroid drugs and AAV is relatively common, few cases triggered by Tapazole have been described, and little is known about how…
As President Trump signed the recently passed Right to Try legislation into law in a White House ceremony, Jordan McLinn of Indianapolis tried twice to embrace him. The third time, 9-year-old Jordan finally got the hug he wanted — as well as a kiss on the forehead. The video of…
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