People with ANCA-associated vasculitis (AAV) have a higher risk of cardiovascular disease, especially in the months immediately following AAV diagnosis, a population-based analysis found. “Our study demonstrates a key ‘high-risk window’ that should prompt careful monitoring for CV [cardiovascular] disease and aggressive risk factor reduction,” the scientists said. The…
News
People over the age of 65 with ANCA-associated vasculitis (AAV) have worse mortality outcomes than younger patients, but kidney failure is not greater in this group, according to a recent study. These worse outcomes were associated with lower levels of hemoglobin — the protein responsible for carrying oxygen in…
People with ANCA-associated vasculitis (AAV) adopt a range of strategies that help them to better cope with the condition on their own, but several areas of self-management could be addressed more immediately through conversations with their physicians, a study found. The study, “Addressing the transition to a chronic…
The case of a man in Saudi Arabia with granulomatosis with polyangiitis (GPA), a form of ANCA-associated vasculitis, highlights the difficulties that can occur in diagnosing this disease, a case study reports. The report is one of the few documented instances of GPA in Saudi Arabia. The study, “…
Blood levels of progranulin — a protein involved in cell development, cell growth, and wound healing — may predict the severity of ANCA-associated vasculitis (AAV), a new observational study suggests. According to researchers, serum progranulin, or the protein’s levels in the bloodstream, “could be used as a predictive marker…
Plasma exchange and extracorporeal membrane oxygenation or ECMO — the use of an artificial lung — are two interventions that may benefit patients with severe ANCA-associated vasculitis (AAV) linked with pulmonary hemorrhage, a potentially life-threatening condition in which blood starts to build up in the lungs, a case…
Over 230 national organizations signed a letter urging all 50 U.S. state governors to “maintain and expand” flexibility with licensure requirements for the duration of the COVID-19 pandemic to ease access to care. During the pandemic, governors used emergency authority to waive certain state licensure requirements, giving healthcare providers…
A committee of the European Medicines Agency has recommended approving Tavneos (avacopan) as an add-on therapy for adults with severe, active microscopic polyangiitis (MPA) or granulomatosis with polyangiitis (GPA), the two most common types of ANCA-associated vasculitis. This recommendation from the Committee for Medicinal Products for Human Use…
A new classification system, based on the underlying cause of disease, may be necessary to better understand ANCA-associated vasculitis (AAV) and other disorders characterized by inflammation in the blood vessels. That’s according to a team led by scientists at Aarhus University, in Denmark, who published their idea for the…
After an initial biopsy shows signs of active ANCA-associated vasculitis (AAV) affecting the kidneys, repeat biopsies are better at determining active disease than standard measures of kidney function, a new observational study reports. Such repeat kidney biopsies may help determine treatment response and personalize care plans for people with…
Recent Posts
- Even with ANCA vasculitis, we can be awe-struck by our own bodies
- Current adult AAV criteria better at classifying the disease in children
- Nkarta cell therapy trial may soon offer outpatient treatment option in AAV
- The importance of rest in managing vasculitis-related fatigue
- Diagnostic delays in AAV vary by subtype and disease features