Lindsey Shapiro, PhD, science writer —

Lindsey earned her PhD in neuroscience from Emory University in Atlanta, where she studied novel therapeutic strategies for treatment-resistant forms of epilepsy. She was awarded a fellowship from the American Epilepsy Society in 2019 for this research. Lindsey also previously worked as a postdoctoral researcher, studying the role of inflammation in epilepsy and Alzheimer’s disease.

Articles by Lindsey Shapiro

AAV Emerges in Boy Using Levamisole to Treat Kidney Disease

ANCA-associated vasculitis (AAV) emerged as a side effect of levamisole given for years to treat a 15-year-old boy with idiopathic nephrotic syndrome, according to a case report. “By reporting this case, we want to raise awareness among clinicians regarding a rare complication of treatment with Levamisole that is often…

Lung, ENT Involvement, Steroid Use Reduced With Tavneos: ADVOCATE

Tavneos (avacopan) reduced respiratory, ear, nose, and throat (ENT) involvement among people with ANCA-associated vasculitis (AAV), but did not significantly outperform prednisone in its ability to do so, according to a substudy of the larger Phase 3 ADVOCATE trial. The treatment also significantly lowered patients’ reliance on glucocorticoid…

Stopping Neutrophil Webs May Benefit Patients With Lung Fibrosis

Antimicrobial webs produced by neutrophils — immune cells that respond quickly to bodily injury — may be implicated in the development of ANCA-associated vasculitis (AAV) accompanied by lung scarring (fibrosis), a recent review of several published studies revealed. These webs of DNA and antimicrobial proteins are known as neutrophil…

5 Genes Identified as Biomarkers in AAV-related Kidney Damage

Genetic biomarkers and immune pathways related to kidney damage in people with ANCA-associated vasculitis (AAV) were identified in a recent study. The five identified biomarker genes may be involved in the progression of kidney damage through immune system signaling, its researchers said. The study, “Identification of Hub Biomarkers and…