News ChemoCentryx Secures $100M Credit to Support Avacopan’s Approval Applications, Potential Commercial Launch

News Elevated Microparticle Levels in AAV Patients Mark Higher Risk of Blood Clots, Study Suggests

News S. aureus Bacterium in Nose Not Linked with AAV Relapses, Study Suggests

News ‘Favorable Outcomes’ with Treatment Likely for Older Adults with AAV, Study Finds

News Rituxan Superior to Azathioprine in Preventing AAV Relapse, Phase 3 Trial Suggests

News Mitochondrial DNA May Serve as Urinary Biomarker of Kidney Damage, Chinese Study Suggests

News Nutritional Status Score Can Help Predict Prognosis of AAV Patients, Study Says

News HHS Secretary Alex Azar Touts White House Efforts to Cure Rare Diseases

News Inflammation Seems to Play Role in Bad Cholesterol Levels, Research Suggests

News Disease Activity and Quality of Life Influence Work Productivity of AAV Patients, Study Finds

News Avacopan Shows Superiority Over Steroids to Treat AAV in Phase 3 ADVOCATE Trial

News Smoking Raises Person’s Risk of AAV, Large US Study Suggests

News High-dose Glucocorticoids Common for AAV Patients in Europe, But Response Is Limited, Study Reports

News Rare Disease Film Festival Highlights Patient and Researcher Unity

News Patients With SLE, GPA Have High Long-Term Survival Rates After Kidney Transplant, Study Shows

News ANCA-Associated Vasculitis can Result in Appendicitis Without Other Systemic Symptoms, Case Report Shows

News Fewer Relapses, Lower Steroid Doses After Dialysis in Japanese AAV Patients, Study Reports

News Japanese Team Suggests Activin A as New Biomarker for Renal Damage in AAV Patients

News Small RNA Molecule miR-142-3p May Impair Immune T-Cell Function in GPA, Study Finds

News Mutant Blood Cells Relatively Common in AAV Patients and Carry Risks and Benefits, Study Suggests

News Young Musician’s ‘Violin for Vasculitis’ Charity Strikes a Chord with Fellow Patients

News AAV Linked to Bleeding and Iron Deposits in Lungs in Case Study

News Repeated Doses of Rituximab May Improve AAV Patients’ Response to the Medication, Study Suggests

News Bacterial Infections, Especially in Lungs, Common in AAV Patients in Southern China, Study Reports

News Childhood Onset AAV Affects Multiple Organs at Diagnosis, May Be Managed with Rituximab, Study Suggests

News No Benefit in Add-on Pulse Methylprednisolone for AAV Patients Needing Dialysis, Study Finds

News AAV Patients on Immunosuppressants at Higher Risk of Cancer, Especially Skin Cancer, Swedish Study Finds

News FDA Approves Rituxan for Children and Adolescents with GPA, MPA

News Low-dose Glucocorticoid Regimen May Effectively Treat AAV in Elderly Patients, Study Suggests

News NORD 2019 Rare Disease Summit Set for Oct. 21-22 in Washington, DC

News AAV Patients Treated with Immunosuppressive Therapy More Likely to Develop Infectious Complications

News GPA Management Should Not Be Based on ANCA Levels Alone, Study Suggests

News Risk Factors for Deep-vein and Other Blood Clots in AAV Patients ID’d in Study

News Neurological Symptoms in AAV Patients Do Not Impact Likely Long-term Survival, Study Reports

News Lung Ultrasound Accurately Detects Lesions in AAV, Study Shows

News Small Particles May Serve as Blood Biomarker of Kidney Problems in AAV, Study Suggests

News AAV and Lupus in Woman with Unusual Kidney Damage Described in Case Report

News New Mouse Model of AAV May Reveal Role of Specific DNA Regions

News Study Identifies AAV-associated Genetic Variants in Chinese Population

News Isolated Acute Sinusitis Might Indicate GPA, Case Report Suggests

News New Index Calculates AAV Severity at Diagnosis and Predicts Mortality, Study Says

News ‘Disorder’ Film Festival Offers Look at Siblings Touched by Rare Diseases

News Best Methods for Detecting ANCAs in AAV Patients Identified in Study from China

News At NY Genome Center, Legal Expert Presents Ethical Dilemmas in Gene Editing

News Cocaine Use Can Trigger ANCA Production, AAV-like Kidney Symptoms, Case Reports Show

News Connective Tissue Diseases More Common in AAV Patients with Kidney Involvement Than Thought, Study Reports

News Improved Classification Systems Needed for AAV, Study Shows

News Intravenous Immunoglobulin Quickly Lowers Disease Activity in AAV Patients, Review Study Finds

News Nebraska’s Neena Nizar Seeks Cure for Jansen’s, One of World’s Rarest Diseases

News Immune Cell Profile Classification Useful for Prognosis, Treatment of AAV, Study Finds

News ANCA Autoantibodies Produced in Healthy People, Study Shows

News AAV Involving Kidneys May Not Always Start in Glomeruli, Case Report Suggests

News Study Identifies Factors for Renal Recovery for AAV Patients on Dialysis for Kidney Damage

News Development of Oral Candidiasis Predicts Severe Infections in AAV Patients Receiving Immunosuppressants, Study Shows

News Treating ANCA Vasculitis in Cancer Patients Best Approach, Case Study Suggests

News Oklahoma Ranks Lowest on Programs Key to Rare Diseases on NORD’s 2019 State Report Card

News Rare Disease Groups Seek Public Support to Renew Newborn Screening Act in Senate

News Levels of Rheumatoid Factor May Mark Two Distinct Types of EGPA, Study Says

News FDA Approves Rituxan Biosimilar Ruxience for 2 ANCA Vasculitis Subtypes

News Interleukin-6 Levels Predict Severe Relapses in ANCA Vasculitis Patients on Rituximab, Study Reports

News Antimicrobial Traps in AAV Patients Differ From Those With SLE, Study Says

News Alterations in Kidney Cells Could Predict Excess Protein in Urine, Study Suggests

News Inflammatory Proteins May Serve as Biomarkers of Early Disease, Kidney Damage in AAV, Study Suggests

News European Initiative Targets Diagnosis, Treatment of Rare Diseases

News Fluid Buildup Around Heart Leads to Finding of Vasculitis Subtype EPGA, Case Study Reports

News High Blood Pressure and Other Cardiovascular Risks Prevalent in ANCA Vasculitis Patients, Researchers Say

News Lipid Level Increases Could Indicate Cardiovascular Risk in ANCA Vasculitis Subsets, Study Reports

News Fatigue Persists at High Levels in Some AAV Patients Despite Treatment, Study Shows

News AIMP1 Blood Levels Might Indicate Disease Severity in AAV Patients, Study Reveals

News AAV Patients With Low Complement Levels Experience Greater Kidney Damage, Study Reports

News World’s First Alport Stamp Is Macedonian Mom’s Latest Win for Rare Disease Patients

News Rituxan May Help Treat Aorta Inflammation in AAV, Case Report Suggests

News Complement System Plays Role in ANCA-associated Vasculitis, Regardless of ANCA Subtype, Study Says

News Major Infections Are Main Cause of Death in AAV Patients, Study Finds

News NORD Honors Industry, Patient Advocates at Rare Impact Awards Gala

News AAV Neutrophils Show Increased Activation of the Alternative Complement System, Study Finds

News Study: Rituxan Reduces Disease Activity in EGPA, But Relapses Stay High

News Eurordis Unveils Integrated-care Initiative for Rare Disease Patients

News Rituxan Is Cost-effective for ANCA-associated Vasculitis, Study Says

News ‘Rare Barometer’ Program Helps Eurordis Shape EU Rare Disease Policy

News Proteins Linked to Neutrophil Clearance Altered in GPA Patients, Study Finds

News FDA Grants Priority Review to Rituxan Plus Glucocorticoids for Children with GPA and MPA

News FDA Approves Autoinjector and Pre-filled Syringe for Self-Administration of Nucala

News High Levels of MPO-ANCA Antibodies Linked to Poor Kidney Function in Long-term, Study Says

News AAV Patients More Likely to Develop Thyroid Disease, Korean Study Finds

News Plasma Exchange Effective for AAV Patients with Severe Renal Damage, Study Reports

News BVAS and FFS Both Useful Tools for Predicting AAV Prognosis and Choosing Therapy, Study Says

News Rituxan-Soliris Combo May Replace Glucocorticoids in Treatment of Severe AAV, Case Report Suggests

News Blood in Urine Linked to Higher Risk of Kidney Disease Relapse in AAV Patients, Study Finds

News Agency Unveils RaDaR to Help Patient Groups Develop Rare Disease Registries

News Urinary Gremlin Protein Levels a Potential Biomarker for ANCA-associated Renal Vasculitis, Study Finds

News First Patient Dosed in European Trial Testing IFX-1 Investigational Therapy, InflaRx Announces

News Rare Diseases Constitute a ‘Public Health Issue,’ NCATS Director Warns

News ChemoCentryx on Track to Present Topline Data From its Ongoing ADVOCATE Phase 3 Trial on Avacopan

News Cerebral Small Vessel Disease Can Be Detected Before Diagnosis of MPO-AAV, Study Suggests

News Stopping Immunosuppressants May Be OK for Some ANCA Vasculitis Patients, Study Suggests

News Tumors in Thymus May Cause ANCA-associated Vasculitis, Case Report Suggests

News Lupus Nephritis Patients with ANCA Antibodies Have More Aggressive Kidney Disease, Case Report Suggests

News Nonprofit Group Works to Raise Rare Disease Awareness in India

News Expanded ANCA Testing May Improve AAV Diagnosis, Classification, Study Says