Updates

October 17, 2019October 17, 2019
AAV Linked to Bleeding and Iron Deposits in Lungs in Case Study

ANCA-associated vasculitis (AAV) can cause recurrent bleeding in the lungs, which manifest as hemosiderosis — an excessive accumulation of iron deposits in tissues ... Read more
October 16, 2019
Repeated Doses of Rituximab May Improve AAV Patients’ Response to the Medication, Study Suggests

Administering rituximab repeatedly may improve the response of patients with ANCA-associated vasculitis (AAV) to the medication, a study says. The findings were reported ... Read more
October 10, 2019
Bacterial Infections, Especially in Lungs, Common in AAV Patients in Southern China, Study Reports

Infection is a common complication of ANCA-associated vasculitis (AAV) that tends to develop within six months of diagnosis, and in cases of “mixed” ... Read more
October 8, 2019
Childhood Onset AAV Affects Multiple Organs at Diagnosis, May Be Managed with Rituximab, Study Suggests

ANCA-associated vasculitis (AAV) with childhood onset often affects multiple organs, showing symptoms at diagnosis in the ear, nose, and throat, as well as ... Read more
October 7, 2019October 7, 2019
No Benefit in Add-on Pulse Methylprednisolone for AAV Patients Needing Dialysis, Study Finds

Adding methylprednisolone pulse therapy to standard induction therapy does not appear to have any particular benefit for people with severe ANCA-associated vasculitis (AAV) ... Read more

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News

AAV Patients on Immunosuppressants at Higher Risk of Cancer, Especially Skin Cancer, Swedish Study Finds
October 3, 2019October 3, 2019
People with ANCA-associated vasculitis (AAV) are much more likely to develop a type of ...
News

FDA Approves Rituxan for Children and Adolescents with GPA, MPA
October 1, 2019October 4, 2019
The U.S. Food and Drug Administration (FDA) has approved Rituxan (rituximab), in combination with ...
News

Low-dose Glucocorticoid Regimen May Effectively Treat AAV in Elderly Patients, Study Suggests
September 30, 2019September 30, 2019
A low-dose glucocorticoid regimen, in which intravenous methylprednisolone (a type of steroid) is not routinely ...
News

NORD 2019 Rare Disease Summit Set for Oct. 21-22 in Washington, DC
September 27, 2019
Next month’s annual conference of the National Organization for Rare Disorders (NORD) in Washington, ...
News

AAV Patients Treated with Immunosuppressive Therapy More Likely to Develop Infectious Complications
September 26, 2019
Patients with ANCA-associated vasculitis (AAV) treated with immunosuppressive agents have a higher risk of ...
News

GPA Management Should Not Be Based on ANCA Levels Alone, Study Suggests
September 24, 2019
In granulomatosis with polyangiits (GPA) patients, the levels of anti-neutrophil cytoplasmic autoantibodies (ANCAs) — ...

Risk Factors for Deep-vein and Other Blood Clots in AAV Patients ID’d in Study
September 23, 2019
People with ANCA-associated vasculitis (AAV) are at a greater risk of venous thromboembolism — ...
Neurological Symptoms in AAV Patients Do Not Impact Likely Long-term Survival, Study Reports
September 19, 2019
Almost half of patients diagnosed with ANCA-associated vasculitis (AAV) showed neurological symptoms in a ...
Lung Ultrasound Accurately Detects Lesions in AAV, Study Shows
September 17, 2019
Small Particles May Serve as Blood Biomarker of Kidney Problems in AAV, Study Suggests
September 16, 2019
AAV and Lupus in Woman with Unusual Kidney Damage Described in Case Report
September 12, 2019September 30, 2019
New Mouse Model of AAV May Reveal Role of Specific DNA Regions
September 10, 2019

Study Identifies AAV-associated Genetic Variants in Chinese Population
September 9, 2019
Variants in immune-related genes may make certain people more or less susceptible to anti-neutrophil ...
Isolated Acute Sinusitis Might Indicate GPA, Case Report Suggests
September 5, 2019
New Index Calculates AAV Severity at Diagnosis and Predicts Mortality, Study Says
September 3, 2019
‘Disorder’ Film Festival Offers Look at Siblings Touched by Rare Diseases
September 2, 2019August 30, 2019

Best Methods for Detecting ANCAs in AAV Patients Identified in Study from China
August 29, 2019August 29, 2019
After examining 12 established methods for detecting antineutrophil cytoplasmic antibodies (ANCAs), researchers in China ...
At NY Genome Center, Legal Expert Presents Ethical Dilemmas in Gene Editing
August 28, 2019
Cocaine Use Can Trigger ANCA Production, AAV-like Kidney Symptoms, Case Reports Show
August 27, 2019

News

Connective Tissue Diseases More Common in AAV Patients with Kidney Involvement Than Thought, Study Reports
August 26, 2019September 30, 2019
More people with ANCA-associated vasculitis (AAV), including those with kidney involvement, also have connective tissue ...
News

Improved Classification Systems Needed for AAV, Study Shows
August 22, 2019
The autoimmune condition ANCA-associated vasculitis (AAV) needs improved classification systems that can better predict ...
News

Intravenous Immunoglobulin Quickly Lowers Disease Activity in AAV Patients, Review Study Finds
August 20, 2019
Intravenous immunoglobulin (IVIG) therapy leads to a fast and significant reduction in disease activity, ...
News

Nebraska’s Neena Nizar Seeks Cure for Jansen’s, One of World’s Rarest Diseases
August 20, 2019August 19, 2019
Imagine living your whole life with a painful disease so rare that only 25 ...
News

Immune Cell Profile Classification Useful for Prognosis, Treatment of AAV, Study Finds
August 19, 2019
Dividing people with active ANCA-associated vasculitis (AAV) into different subgroups may be useful for ...
News

ANCA Autoantibodies Produced in Healthy People, Study Shows
August 13, 2019September 4, 2019
Healthy individuals also produce a type of self-reactive antibodies — termed IgM ANCA — ...

January 11, 2018

Early Diagnosis of AAV Symptoms Decreases Risk of Renal Damage, Mortality

News

A retrospective study has found an association between the length of prodromal phase – where patients experience non-specific symptoms before more specific disease signs develop – and mortality in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) patients. This finding ... Read more

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