Updates

September 21, 2018September 21, 2018
#NORDSummit – More Than 700 Expected to Attend Oct. 15-16 Rare Disease Summit in Washington

More than 700 medical experts, pharmaceutical executives, patient advocates, and others are expected to converge on Washington, D.C., next month for the 2018 NORD ... Read more
September 20, 2018September 20, 2018
ANCA Vasculitis Maintenance Therapy Imuran Causes Allergic Reaction in Kidneys, Case Report Shows

A patient taking Imuran (azathioprine) to treat his ANCA-associated vasculitis experienced an acute allergic reaction to the therapy which manifested as a kidney inflammation. Researchers ... Read more
September 18, 2018
Cigarettes Caused Smoker with Interstitial Lung Disease to Produce ANCA Antibodies, Report Says

In patients with interstitial lung disease, cigarette smoking may sometimes cause the production of ANCA associated antibodies — a hallmark of ANCA-associated vasculitis — without ... Read more
September 13, 2018
Head and Neck Symptoms Can Indicate GPA, So Clinicians Must Be Watchful

Alterations in the nasal cavity mucosa and throat often are primary symptoms of granulomatosis with polyangiitis (GPA) and it is critical that otolaryngologists ... Read more
September 10, 2018
Antiviral Therapy May Reduce Risk of Infection in AAV Patients, Clinical Study Suggests

Antiviral therapy prevents silent reactivation of cytomegalovirus (CMV) in ANCA-associated vasculitis (AAV) patients and improves patients’ immune responses, a proof-of-concept clinical study shows. These results ... Read more

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News

AAV Patients with Kidney Condition Have Worse Survival Rates, Population-based Study Finds
September 6, 2018
Patients with ANCA-associated vasculitis who have a kidney condition called glomerulonephritis have higher mortality ...
News

Rituxan, Corticosteroids Were Successful in Treating Patient with EGPA, Case Study Reports
September 4, 2018
A case report of a patient with eosinophilic granulomatosis with polyangiitis (EGPA), with the disease ...
News

Case Report Describes Patient with Muscle Condition Who Developed Acute Kidney Disease Due to Overlapping Vasculitis
August 16, 2018
Patients with dermatomyositis — a condition marked by muscle weakness and a distinctive skin ...
News

Levels of Pro-inflammatory Molecule Can Predict Poor Outcomes in AAV, Study Finds
August 13, 2018
Patients with ANCA-associated vasculitis (AAV) with elevated SDMA — a pro-inflammatory molecule — in their blood ...
News

Ratio Between 2 Types of Immune Cells Can Predict Risk of Relapse in ANCA Vasculitis Patients, Study Finds
August 7, 2018
The ratio of neutrophils to lymphocytes — two types of immune cells — can ...
News

While Uncommon, AAV Patients May Have Overlapping Autoimmune Disease, Study Suggests
August 6, 2018
Roughly 1 in 10 patients with ANCA-associated vasculitis have another overlapping autoimmune disease, such ...

FDA Clears 2 PerkinElmer’s Assays to Help Diagnose ANCA Vasculitis
August 2, 2018
The U.S Food and Drug Administration (FDA) cleared two assays to be used in ...
Biopsy Combined with Other Tests Can Better Predict Kidney Survival, Study Finds
July 31, 2018
Patients with ANCA-associated vasculitis (AAV) who have renal symptoms might benefit from a kidney biopsy ...
Renal Artery Rupture a Rare Complication of Microscopic Polyangiitis, Case Study Reports
July 30, 2018
Aortic Aneurysm Occurred as Complication of Granulomatosis with Polyangiitis, Case Report Says
July 26, 2018
Kidney Biopsies Help Predict End-Stage Disease in Older AAV Patients, Study Shows
July 23, 2018
ANCA Vasculitis Can Develop in Scleroderma Patients in Rare Cases, Study Reports
July 19, 2018

Pregnant Women Who Develop AAV May Safely Be Treated with Rituxan, Case Report Suggests
July 16, 2018
Pregnant women who develop ANCA-associated vasculitis (AAV) may safely receive Rituxan (rituximab) and corticosteroids, a ...
Leptin Deficiency Can Lead to Development of AAV, Case Study Suggests
July 10, 2018
Defense Processes of Neutrophils Linked to Active AAV Disease, Study Finds
July 9, 2018
Antibiotics Can Help AAV Patients on Rituxan Lower Risk of Severe Infections, Study Finds
July 5, 2018July 5, 2018

InflaRx Set to Launch Phase 2 Trial Testing IFX-1 in AAV Patients Following FDA Approval
July 3, 2018
InflaRx will soon begin a Phase 2 clinical trial assessing the safety and effectiveness of ...
Researchers Need to Better Understand Differences in Eosinophilic Granulomatosis with Polyangiitis Symptoms in Children and Adults, Study Suggests
July 2, 2018July 2, 2018
New Subtype of ANCA-associated Vasculitis Proposed by Researchers in China
June 28, 2018

News

Narrowing of Respiratory Airways a Common, Serious Complication of GPA, Study Shows
June 26, 2018
Tracheobronchial stenosis, a lung complication characterized by the narrowing of the trachea and bronchi, ...
News

GPA Often Affects Eye, Requiring Care from Ophthalmologist, Study Suggests
June 25, 2018
Granulomatosis with polyangiitis (GPA) patients often experience eye involvement, suggesting an ophthalmologist is necessary ...
News

Interstitial Lung Disease May Trigger Microscopic Polyangiitis in Some Patients, Case Report Suggests
June 21, 2018
Interstitial pneumonia may trigger the production of anti-neutrophil cytoplasmic antibodies (ANCA) and lead to ...
News

Immunosuppressants Linked to Reduced Risk of Relapses in Subset of AAV Patients
June 19, 2018
Treatment with immunosuppressants does not improve kidney function, but is associated with reduced risk ...
News

Study Reports First Case of GPA Involving Entire Gastrointestinal Tract
June 18, 2018June 18, 2018
Mexican researchers reported for the first time a patient with granulomatosis with polyangiitis (GPA) ...
News

Immunosuppressive Treatment of ANCA Vasculitis May Increase Patients’ Risk of Late-onset Pneumonia
June 14, 2018June 14, 2018
Patients with ANCA-associated vasculitis using an immunosuppressive therapy may be at risk of late-onset ...

January 11, 2018

Early Diagnosis of AAV Symptoms Decreases Risk of Renal Damage, Mortality

News

A retrospective study has found an association between the length of prodromal phase – where patients experience non-specific symptoms before more specific disease signs develop – and mortality in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) patients. This ... Read more

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