News Urinary Gremlin Protein Levels a Potential Biomarker for ANCA-associated Renal Vasculitis, Study Finds

News First Patient Dosed in European Trial Testing IFX-1 Investigational Therapy, InflaRx Announces

News Rare Diseases Constitute a ‘Public Health Issue,’ NCATS Director Warns

News ChemoCentryx on Track to Present Topline Data From its Ongoing ADVOCATE Phase 3 Trial on Avacopan

News Cerebral Small Vessel Disease Can Be Detected Before Diagnosis of MPO-AAV, Study Suggests

News Stopping Immunosuppressants May Be OK for Some ANCA Vasculitis Patients, Study Suggests

News Tumors in Thymus May Cause ANCA-associated Vasculitis, Case Report Suggests

News Lupus Nephritis Patients with ANCA Antibodies Have More Aggressive Kidney Disease, Case Report Suggests

News Nonprofit Group Works to Raise Rare Disease Awareness in India

News Expanded ANCA Testing May Improve AAV Diagnosis, Classification, Study Says

News 2 Molecules May Serve as Potential Biomarkers for Disease Activity in EGPA Patients, Study Suggests

News Rituxan Deemed Safe, Effective for Refractory or Relapsing GPA Patients

News Heart Valve Damage Might Be Cause of Breathing Difficulties in ANCA-Associated Vasculitis, Case Report Says

News Donor Antibodies Given Intravenously May Treat ANCA Vasculitis, Early Study Reports

News Anti-NET Antibodies May Prevent Normal Degradation of Antimicrobial Traps in MPA Patients, Study Says

News Blood Biomarker Able to Quickly Diagnose Active ANCA Vasculitis as Distinct from Infections, Study Reports

News Eosinophils Play Inflammatory Role in Patients with GPA and MPA, Study Suggests

News Most AAV Patients with Orbital Mass Respond Poorly to Treatment, Study Finds

News PR3-ANCA Vasculitis May Cause Internal Organ Damage Due to Inadequate Blood Supply, Case Report Suggests

News New Diagnostic Criteria May Replace Nasal Biopsy in Suspected GPA with Rhinosinusitis, Study Suggests

News Antiphospholipid Antibodies Linked to Risk of Blood Clots in AAV Patients

News Interleukin-21 Levels May Indicate Disease Activity in AAV Patients, Pilot Study Suggests

News Eye Problems May Be Early GPA Symptom; Rituxan Helps in Recurrent Cases

News Case Report Describes Rare Coexistence of Chronic Liver Condition and MPA

News Osteoporosis Treatment Denosumab May Cause ANCA Vasculitis, Case Report Suggests

News Brexit Could Have Real Effects for UK Rare Disease Patients, Experts Warn

News Small Particles Produced by Platelets May Worsen Inflammation in AAV, Study Contends

News Moral Dilemmas Complicate Treatment of Rare Diseases, Says Israeli Bioethicist

News Dividing AAV According to Antibodies Provides No Further Benefit for Prognosis, Study Reports

News Rise in MPO-ANCA Antibodies After Remission May Predict Relapse

News Antibody Fragment May Be Used to Treat ANCA Vasculitis, Study Reports

News NIH Rare Disease Day Highlights Joint Networks Advancing Array of Research

News Low-dose Radiotherapy Could Treat Cancer Caused by GPA Lesions, Case Report Suggests

News MabThera Induction Treatment for AAV Shows Real-world Effectiveness, Study Reports

News Link Exists Between EGPA and Clotting Disease in Small Blood Vessels, Report Suggests

News WODC 2019 Organizers Expect 1,200 to Attend Rare Disease Conference in April

News Study: IV Methylprednisolone Doesn’t Benefit, May Harm AAV Patients

News Improved Outcomes in AAV Patients May Be Due to Earlier Diagnosis, Better Management, Study Suggests

News New Test May Help Determine Disease Activity in GPA Patients, Study Reports

News Vienna to Host RARE2019 Meeting on Rare Diseases

News Patients Testing Positive for ANCA Vasculitis Antibodies May Not Have the Disease, Study Shows

News Testicular Pain and Swelling Can Be Initial Sign of ANCA-associated Vasculitis, Case Report Finds

News Reduced Muscle Strength Leads to Poor Quality of Life in ANCA Vasculitis Patients, Study Says

News Abnormal Antimicrobial Traps in Lesions May Be Linked to AAV Development, Study Says

News Lower Doses of Rituxan Equally Effective at Controlling AAV, Study Suggests

News Patients, Family and Friends to Take Part in Variety of Rare Disease Day Events Worldwide

News Radiotherapy Should Be Done Carefully on GPA Patients with Cancer to Avoid Complications, Case Study Suggests

News PredictImmune Granted Patent in Canada for Methods to Predict Autoimmune Disease Progression

News ICD-10 Codes, ‘Really Important’ to Rare Disease Patients, Soon Up for Fresh Consideration

News Belimumab Maintenance Fails to Delay Relapse in AAV Patients, Phase 3 Trial Suggests

News New Plans Announced for Full Marketing Approval of Avacopan as Treatment for ANCA Vasculitis

News ANCA Testing Useful but Not Sufficient for AAV Diagnosis in Patients with Neurological Symptoms, Study Says

News Gene Expression Analysis of AAV Tissue Sheds New Light on Disease Progression, Study Finds

News Study Finds Predictors of Renal Outcomes in Children with ANCA Vasculitis

News Mycophenolate Mofetil Can Replace Cyclophosphamide at Inducing Remission in Some AAV Patients, Clinical Trial Suggests

News Markers of Renal Outcomes in Subclass of ANCA Vasculitis Patients Found, Study Says

News Patient Develops AAV Due to Familial Mediterranean Fever, Case Study Shows

News Case Report Shows for First Time That AAV May Also Affect Brain, Spinal Cord

News Omalizumab May Reduce Asthma Symptoms and Steroid Requirement in EGPA Patients, Study Shows

News Rare Case of GPA/EGPA Overlap Syndrome Highlights Importance of Early Diagnosis

News Study Finds 3 Gene Variants Linked with Poor Outcomes in AAV Patients

News European Union Approves Phase 2 Trial Testing IFX-1 in AAV Patients

News Rare Case of Azathioprine-induced Skin Reaction Seen in AAV Patient in Case Study

News Rising Healthcare Costs Strain EU Budgets Even as New Therapies Flourish

News Another Case of AAV Caused by Blood Pressure Medication Hydralazine Reported

News CD64 Levels in Neutrophils Distinguish Infection From Active Disease in AAV, Lupus, Study Reports

News ANCA-associated Vasculitis Can Sometimes Manifest as Progressive Lung Disease, Case Report Suggests

News Early, Severe Infections Strongly Predict Mortality in Older Patients with Kidney Inflammation, Study Shows

News Early Disease Status Predicts Long-term Outcomes in AAV Patients, Study Suggests

News Plasma Exchange Not Seen to Lessen Risk of Death or Kidney Failure in Severe ANCA Vasculitis Patients in Phase 3 Trial

News Rituxan’s Efficacy May Be Linked to It Blocking How B-cells and Certain T-cells Interact, Study Says

News Many ANCA-associated Vasculitis Patients Develop Hypersensitivity to Azathioprine, Study Shows

News Cyclophosphamide and Rituxan May Safely Treat AAV Patients During Pregnancy, Study Finds

News Calprotectin Blood Levels May Work as Biomarker for Tailoring Maintenance Treatments in AAV Patients

News Rare SLE-AAV Overlap Syndrome May Cause Stroke, Case Report Shows

News Woman with Double-Positive Disease Treated with Plasma Exchange Combo, Case Study Shows

News New Classification System Enables Prediction of Kidney Function and Survival in ANCA Glomerulonephritis Patients

News #NORDSummit – Major Issues on Table for Rare Disease Patients in US as Midterm Elections Approach

News Carbon Monoxide, Colder Weather Linked to Rise in AAV Frequency in Large Study from China

News FDA Expands Approval of Rituxan as Remission Maintenance Treatment for GPA and MPA Patients

News Pregnant Women with ANCA-associated Vasculitis More Prone to Complications, Review Shows

News Levamisole-laced Cocaine Led to ANCA Vasculitis and Kidney Damage, Case Report Recounts

News Tailored Rituxan Regimen for ANCA Vasculitis Patients as Effective, Possibly Safer than Fixed-schedule Treatment, Expert Says

News Cocaine Abuse Causes Symptoms that Mimic AAV, Complicating Diagnosis, Case Report Shows

News Advocacy Groups, Doctors Question Rising Prices of Rare Disease Treatments

News Minimal Glucocorticoid Regimen Shows Similar Efficacy, Fewer Adverse Events than Standard Treatments, Study Reports

News Muscle Weakness a Rare Presenting Symptom of ANCA-associated Vasculitis, Case Report Shows

News Atypical ANCAs Do Not Contribute to Vessel Inflammation in Patients with Eye Disease, Study Suggests

News Small-vessel Vasculitides Linked to Worse Prognosis During ICU Stays, Polish Study Finds

News Measuring ANCA Levels in Sputum May Improve EPGA Diagnosis, Management, Study Suggests

News Low C3 Levels at Diagnosis Can Predict Severity of ANCA-associated Vasculitis, Poor Kidney Outcomes, Study Finds

News #NORDSummit – More Than 700 Expected to Attend Oct. 15-16 Rare Disease Summit in Washington

News ANCA Vasculitis Maintenance Therapy Imuran Causes Allergic Reaction in Kidneys, Case Report Shows

News Cigarettes Caused Smoker with Interstitial Lung Disease to Produce ANCA Antibodies, Report Says

News Head and Neck Symptoms Can Indicate GPA, So Clinicians Must Be Watchful

News Antiviral Therapy May Reduce Risk of Infection in AAV Patients, Clinical Study Suggests

News AAV Patients with Kidney Condition Have Worse Survival Rates, Population-based Study Finds

News Rituxan, Corticosteroids Were Successful in Treating Patient with EGPA, Case Study Reports

News Case Report Describes Patient with Muscle Condition Who Developed Acute Kidney Disease Due to Overlapping Vasculitis

News Levels of Pro-inflammatory Molecule Can Predict Poor Outcomes in AAV, Study Finds