Author Archives: Marta Figueiredo PhD

Antiviral Therapy May Reduce Risk of Infection in AAV Patients, Clinical Study Suggests

Antiviral therapy prevents silent reactivation of cytomegalovirus (CMV) in ANCA-associated vasculitis (AAV) patients and improves patients’ immune responses, a proof-of-concept clinical study shows. These results suggest that antiviral therapy may reduce the risk of infection in these patients. The study, “Subclinical Reactivation of Cytomegalovirus Drives CD4+CD28null T-Cell Expansion…

High-dose Glucocorticoid Pulses May Improve Severe Kidney Condition of AAV Patients, Study Indicates

Patients with severe kidney injury stemming from anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) may benefit from intravenous glucocorticoid pulses, a study indicates. The high-dose treatment helped Chinese patients get off dialysis and showed a tendency toward  increasing their survival, researchers found. They published their findings in the journal BMC Nephrology.