A combination of rituximab, prednisone, and tacrolimus effectively treated a recurrence of anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) after a kidney transplant, a case study reported. The case highlights the importance of closely monitoring AAV patients on immunosuppressive therapy with belatacept, particularly when a kidney injury follows a kidney…
Up to six months of treatment with rituximab led to disease remission in about two-thirds of Japanese patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), a study found. Further, people in Japan with these two types of ANCA-associated vasculitis (AAV) who were given rituximab as a…
The AstraZeneca COVID-19 vaccine may have triggered kidney inflammation linked to ANCA-associated vasculitis (AAV) in a 51-year-old woman, according to a case report. “Due to the temporal association between the application of ChAdOx1 nCoV-19 vaccine and the onset of renal [kidney] function decline in a previously healthy patient, it…
Poor lung function and high levels of inflammatory biomarkers in the bloodstream were found to be risk factors for acute exacerbation — an episode of sudden symptom worsening — in patients with antineutrophil cytoplasmic antibody (ANCA)-associated interstitial lung disease. That’s according to a new study, “Acute exacerbation…
A 16-year-old girl developed granulomatosis with polyangiitis (GPA), a type of anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), after being infected with SARS-COV-2, the virus that causes COVID-19, according to a recent case report. Hers is the fourth known case of pediatric-onset AAV following COVID-19 infection, suggesting the virus could…
Horizon Therapeutics has launched its #RAREis Representation program aimed at increasing diversity, equity, and inclusion among patients with rare diseases. There are about 400 million people worldwide living with a rare disease; for many of them, access to diagnosis, care, and treatments can be challenging. Accessing better care depends on…
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