Somi Igbene, PhD, science writer —

Somi graduated from Imperial College London in 2011 with a PhD in cellular and molecular immunology. She worked as a medical writer at several medical communications agencies in London, including Core Medica. Besides science writing, Somi works as a registered associate nutritionist, helping adults and children improve their diets to prevent type 2 diabetes.

Articles by Somi Igbene

Case of GPA With High Urine Protein Is Unusual

A man with granulomatosis with polyangiitis — a type of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) — and abnormally raised urine protein levels, a sign of kidney disease, has been described in a recent case report. Notably, urine protein levels usually are not significantly elevated in people with granulomatosis…

Complement System Activated Years Before Symptoms in 2 AAV Subtypes

The body’s complement system — comprised of blood proteins that fight infection — is specifically activated in individuals with microscopic polyangiitis and ANCA-associated vasculitis (AAV) with myeloperoxidase (MPO) antibodies years before a patient’s symptoms begin, new research shows. “These findings support differential pathogenic [disease-causing] mechanisms behind” these two AAV…

Progranulin Protein Levels in Blood May Predict AAV Severity

Blood levels of progranulin — a protein involved in cell development, cell growth, and wound healing — may predict the severity of ANCA-associated vasculitis (AAV), a new observational study suggests. According to researchers, serum progranulin, or the protein’s levels in the bloodstream, “could be used as a predictive marker…

Repeat Kidney Biopsies May Help Better Determine Active Disease

After an initial biopsy shows signs of active ANCA-associated vasculitis (AAV) affecting the kidneys, repeat biopsies are better at determining active disease than standard measures of kidney function, a new observational study reports. Such repeat kidney biopsies may help determine treatment response and personalize care plans for people with…