In ANCA-associated vasculitis (AAV), the involvement of the central nervous system (CNS), that is, the brain and spinal cord, is uncommon, but other factors may mimic CNS involvement, a study reports. These so-called mimickers can include AAV disease processes not related to the CNS, other conditions, and drug-related adverse…
People with anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis have elevated levels of certain immune-related proteins in their blood, a new study from Sweden reports. However, different types of AAV involve different immune pathways, depending on the type of antibody involved: proteinase 3, known as PR3, or myeloperoxidase, called MPO.
Ratios of different kinds of blood cells, reflecting inflammation and immune activity, may be a cheap and efficient tool to aid in the diagnosis of ANCA-associated vasculitis (AAV), and in predicting disease activity, a new study from China reports. “While not standalone diagnostic tools, these markers offer valuable support…
The most common neurological symptoms of ANCA-associated vasculitis (AAV) among patients in a single center in Columbia — regardless of disease type — were headache and objective signs of damage to nerves outside the brain and spinal cord, a study showed. That said, the researchers found a vast array…
ANCA-associated vasculitis (AAV) therapy Tavneos (avacopan) is at least as effective as the glucocorticoid prednisone at inducing disease remission, reducing relapse rates, and improving kidney function and quality of life in patients with kidney involvement at treatment start. That’s according to new subgroup analyses from the Phase…
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