Katherine Poinsatte, PhD, Science writer —

Treatment with rituximab in children with ANCA-associated vasculitis (AAV) is at least non-inferior to the use of cyclophosphamide at inducing disease remission or low disease activity among pediatric patients, according to data from a large international observational study. The researchers noted that rituximab treatment was associated with greater…

The long-term use of Nucala (mepolizumab) reduces disease activity and the need for standard glucocorticoids, while improving survival, in people with eosinophilic granulomatosis with polyangiitis (EGPA), the rarest type of ANCA-associated vasculitis (AAV). These are the findings of a real-world study in Japan that compared outcomes between 37…