Posts by: Ashraf Malhas, PhD

News

A retrospective study has found an association between the length of prodromal phase – where patients experience non-specific symptoms before more specific disease signs develop – and mortality in antineutrophil ... Read more

December 14, 2017

Blood in Urine in AAV Patients in Remission May Reflect Renal Damage, Study Finds

News

Persistent hematuria (blood in urine) in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) patients who achieved clinical remission after immunosuppressive therapy is not rare and may be due to chronic renal ... Read more

December 12, 2017December 12, 2017

Severity of Anemia Linked to Poorer Outcomes in Patients with ANCA-Associated Renal Vasculitis

News

A study has found that the severity of anemia in patients with antineutrophil cytoplasmic antibody (ANCA)-associated renal vasculitis is associated with increased renal dysfunction and shorter survival rates. The study, ... Read more

November 13, 2017November 13, 2017

Specific Eye Inflammation Seen as Early Sign of Granulomatosis with Polyangiitis in Case Study

News

A case report finds that necrobiotic xanthogranuloma scleritis, an inflammation of the white part of the eye, could be an early sign of granulomatosis with polyangiitis. The study, “Necrobiotic xanthogranuloma scleritis in a ... Read more

October 31, 2017

Organ Involvement in AAV Patients Better Than Disease Type at Predicting Survival Outcomes, Study Suggests

News

Classifying patients with anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) based on organ involvement at the time patients are first examined has stronger correlation with survival rates, than the customary classification ... Read more

October 26, 2017October 26, 2017

Methotrexate Effective for ANCA-Associated Vasculitis Remission Maintenance Treatment, Study Finds

News

Methotrexate is an effective and safe option for remission maintenance therapy in patients with anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV), a study has found. The study, “Methotrexate versus cyclophosphamide for remission maintenance ... Read more

October 24, 2017

Extended Azathioprine Maintenance Therapy Doesn’t Prevent Relapse in AAV Patients, Study Finds

News

Long-term maintenance therapy with azathioprine (AZA) does not improve relapse rates in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), according to researchers. The study, “Long term azathioprine maintenance therapy ... Read more

October 17, 2017

Changes in Circulating Immune Cells in AAV Linked to Kidney Damage

News

Although certain immune cells are present at lower levels in patients with anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV), it is due to non-specific renal injury rather than the disease itself, ... Read more

October 16, 2017

ANCA–Associated Vasculitis Occurs in Ethnic Groups Differently, Study Finds

News

Different types of ANCA-associated vasculitis occur in different ethnic groups, a study reports. The research, “Global ethnic and geographic differences in the clinical presentations of anti-neutrophil cytoplasm antibody􏰀associated vasculitis,” was ... Read more

October 2, 2017October 2, 2017

Central Nervous System Involvement Seen Not to Affect Survival Rates in GPA Patients, Study Finds

News

A retrospective study has investigated the central nervous system’s (CNS) involvement in granulomatosis with polyangiitis (GPA) in a group of Greek patients. The study found that CNS involvement does not ... Read more