January 15, 2020January 15, 2020
ChemoCentryx Secures $100M Credit to Support Avacopan’s Approval Applications, Potential Commercial Launch
News
ChemoCentryx has secured a credit facility of up to $100 million from Hercules Capital to support the upcoming costs of its new drug ... Read more
January 8, 2020January 8, 2020
Elevated Microparticle Levels in AAV Patients Mark Higher Risk of Blood Clots, Study Suggests
News
People with anti‑neutrophil cytoplasmic antibody (ANCA)‑associated vasculitis (AAV) who have high levels of cellular microparticles in their blood ... Read more
January 6, 2020January 6, 2020
S. aureus Bacterium in Nose Not Linked with AAV Relapses, Study Suggests
News
The presence of the bacterium Staphylococcus aureus was not associated with a higher relapse rate of ANCA-associated vasculitis ... Read more
December 18, 2019December 18, 2019
‘Favorable Outcomes’ with Treatment Likely for Older Adults with AAV, Study Finds
News
Older adults with ANCA-associated vasculitis (AAV) have an overall good prognosis, with a high long-term survival rate, a ... Read more
December 16, 2019December 16, 2019
Rituxan Superior to Azathioprine in Preventing AAV Relapse, Phase 3 Trial Suggests
News
Maintenance therapy with Rituxan (rituximab) is superior to standard care with azathioprine for preventing disease relapses in patients with ... Read more
December 11, 2019December 14, 2019
Mitochondrial DNA May Serve as Urinary Biomarker of Kidney Damage, Chinese Study Suggests
News
Mitochondrial DNA (mtDNA) — DNA specific to mitochondria, the cell’s powerhouses — may be used as a urinary biomarker ... Read more
December 9, 2019December 18, 2019
Nutritional Status Score Can Help Predict Prognosis of AAV Patients, Study Says
News
An instrument that assesses the nutritional status of individuals can be used to predict the prognosis of patients with ... Read more
December 5, 2019
HHS Secretary Alex Azar Touts White House Efforts to Cure Rare Diseases
News
Despite skyrocketing healthcare costs, President Trump is committed to protecting the 30 million or so Americans with rare diseases ... Read more
December 4, 2019December 4, 2019
Inflammation Seems to Play Role in Bad Cholesterol Levels, Research Suggests
News
ANCA-associated vasculitis (AAV) patients have lower levels of low-density lipoprotein (LDL), or “bad cholesterol,” when compared to people ... Read more
December 2, 2019December 2, 2019
Disease Activity and Quality of Life Influence Work Productivity of AAV Patients, Study Finds
News
Work productivity of people with ANCA-associated vasculitis is influenced by their disease activity, the extent of organ damage, ... Read more
November 27, 2019November 27, 2019
Avacopan Shows Superiority Over Steroids to Treat AAV in Phase 3 ADVOCATE Trial
News
Avacopan (CCX168) can effectively improve remission rates, kidney function, and overall quality of life of patients with ... Read more
November 25, 2019November 26, 2019
Smoking Raises Person’s Risk of AAV, Large US Study Suggests
News
Being a former or current cigarette smoker significantly increases the risk of developing ANCA-associated vasculitis (AAV), data from ... Read more

January 15, 2020January 15, 2020

ChemoCentryx Secures $100M Credit to Support Avacopan’s Approval Applications, Potential Commercial Launch

News

ChemoCentryx has secured a credit facility of up to $100 million from Hercules Capital to support the upcoming costs of its new drug application (NDA) for avacopan, its investigational treatment for ANCA-associated vasculitis ... Read more

January 8, 2020January 8, 2020

Elevated Microparticle Levels in AAV Patients Mark Higher Risk of Blood Clots, Study Suggests

News

People with anti‑neutrophil cytoplasmic antibody (ANCA)‑associated vasculitis (AAV) who have high levels of cellular microparticles in their blood may be at higher risk for venous thromboembolism (VTE), a life-threatening ... Read more

January 6, 2020January 6, 2020

S. aureus Bacterium in Nose Not Linked with AAV Relapses, Study Suggests

News

The presence of the bacterium Staphylococcus aureus was not associated with a higher relapse rate of ANCA-associated vasculitis (AAV), a recent study suggests. These results challenge the idea that ... Read more

December 18, 2019December 18, 2019

‘Favorable Outcomes’ with Treatment Likely for Older Adults with AAV, Study Finds

News

Older adults with ANCA-associated vasculitis (AAV) have an overall good prognosis, with a high long-term survival rate, a recent study suggests. Higher frailty scores and elevated levels of C-reactive ... Read more

December 16, 2019December 16, 2019

Rituxan Superior to Azathioprine in Preventing AAV Relapse, Phase 3 Trial Suggests

News

Maintenance therapy with Rituxan (rituximab) is superior to standard care with azathioprine for preventing disease relapses in patients with ANCA-associated vasculitis (AAV) who had achieved remission, results of a ... Read more

December 11, 2019December 14, 2019

Mitochondrial DNA May Serve as Urinary Biomarker of Kidney Damage, Chinese Study Suggests

News

Mitochondrial DNA (mtDNA) — DNA specific to mitochondria, the cell’s powerhouses — may be used as a urinary biomarker of kidney damage in people with ANCA-associated vasculitis (AAV), according to ... Read more

December 9, 2019December 18, 2019

Nutritional Status Score Can Help Predict Prognosis of AAV Patients, Study Says

News

An instrument that assesses the nutritional status of individuals can be used to predict the prognosis of patients with ANCA-associated vasculitis, a study suggests. The study, “Controlling Nutritional Status ... Read more

December 5, 2019

HHS Secretary Alex Azar Touts White House Efforts to Cure Rare Diseases

News

Despite skyrocketing healthcare costs, President Trump is committed to protecting the 30 million or so Americans with rare diseases and ensuring timely, affordable access to lifesaving treatments, the nation’s ... Read more

December 4, 2019December 4, 2019

Inflammation Seems to Play Role in Bad Cholesterol Levels, Research Suggests

News

ANCA-associated vasculitis (AAV) patients have lower levels of low-density lipoprotein (LDL), or “bad cholesterol,” when compared to people without the disease, a study suggests. These differences seemed to dissipate ... Read more

December 2, 2019December 2, 2019

Disease Activity and Quality of Life Influence Work Productivity of AAV Patients, Study Finds

News

Work productivity of people with ANCA-associated vasculitis is influenced by their disease activity, the extent of organ damage, and their health-related quality of life, a study reports. The findings ... Read more