granulomatosis with polyangiitis (GPA)

June 17, 2019

FDA Grants Priority Review to Rituxan Plus Glucocorticoids for Children with GPA and MPA

News

The U.S. Food and Drug Administration (FDA) has granted Priority Review to Rituxan (rituximab) in combination with glucocorticoids for the treatment of children, 2 or older, with granulomatosis with polyangiitis ... Read more

April 18, 2019

Rituxan Deemed Safe, Effective for Refractory or Relapsing GPA Patients

News

Genentech‘s Rituxan (rituximab) is safe and effective to induce and maintain remission in patients with refractory or relapsing granulomatous manifestations (inflamed tissue) due to granulomatosis with polyangiitis (GPA), according to ... Read more

April 16, 2019

Heart Valve Damage Might Be Cause of Breathing Difficulties in ANCA-Associated Vasculitis, Case Report Says

News

While breathing difficulties in ANCA-associated vasculitis patients are often a symptom of worsening vasculitis in their lungs, doctors should also consider cardiac valve involvement — or damage to heart valves — ... Read more

April 8, 2019

Eosinophils Play Inflammatory Role in Patients with GPA and MPA, Study Suggests

News

Eosinophils, a type of immune cell, appear to contribute to the inflammatory process seen in patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), a study shows. The ... Read more

March 21, 2019

Eye Problems May Be Early GPA Symptom; Rituxan Helps in Recurrent Cases

News

Eye problems are a common symptom of granulomatosis with polyangiitis, of which clinicians should be aware as it can be an initial symptom of the disease, a study reports. Most ... Read more

March 5, 2019

Low-dose Radiotherapy Could Treat Cancer Caused by GPA Lesions, Case Report Suggests

News

Tumors caused by granulomatosis with polyangiitis (GPA)-related lesions appear to be especially sensitive to radiation and can be treated effectively with low-dose radiotherapy, a case report suggests. The study, “Radiotherapy ... Read more

January 28, 2019

Gene Expression Analysis of AAV Tissue Sheds New Light on Disease Progression, Study Finds

News

An analysis of the gene expression and gene pathways in different tissues affected by ANCA vasculitis has provided new information about the mechanisms involved in disease progression, a study ... Read more

January 10, 2019

Rare Case of GPA/EGPA Overlap Syndrome Highlights Importance of Early Diagnosis

News

Early identification of granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA) overlap is critical for prognosis, long-term treatment, and management of these two distinct diseases, a case ... Read more

October 23, 2018

FDA Expands Approval of Rituxan as Remission Maintenance Treatment for GPA and MPA Patients

News

The U.S. Food and Drug Administration has approved a label update for Rituxan (rituximab) to include information for patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) who ... Read more

October 11, 2018

Cocaine Abuse Causes Symptoms that Mimic AAV, Complicating Diagnosis, Case Report Shows

News

Inhaling cocaine regularly can cause tissue and blood changes that may mimic those found in patients with ANCA-associated vasculitis (AAV), a case report shows. These findings suggest that in ... Read more

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