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November 6, 2019November 6, 2019

ANCA-Associated Vasculitis can Result in Appendicitis Without Other Systemic Symptoms, Case Report Shows

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Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis can result in inflammation of the appendix — commonly known as appendicitis — without any additional systemic symptoms, researchers report for the first time. ... Read more

November 4, 2019November 4, 2019

Fewer Relapses, Lower Steroid Doses After Dialysis in Japanese AAV Patients, Study Reports

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Dialysis for Japanese patients with kidney disease triggered by ANCA-associated vasculitis led to fewer life-threatening relapses and reduced doses of immunosuppressive steroids, a long-term study suggests. The study, “Long‑term follow‑up ... Read more

October 30, 2019October 30, 2019

Japanese Team Suggests Activin A as New Biomarker for Renal Damage in AAV Patients

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Measuring the levels of activin A protein in the urine can help clinicians identify patients who have renal problems caused by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, Japanese researchers found. ... Read more

October 28, 2019October 28, 2019

Small RNA Molecule miR-142-3p May Impair Immune T-Cell Function in GPA, Study Finds

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High levels of a small RNA molecule called miR-142-3p may impair the function of immune regulatory T-cells in people with granulomatosis with polyangiitis (GPA), a study has found. The ... Read more

October 22, 2019

Mutant Blood Cells Relatively Common in AAV Patients and Carry Risks and Benefits, Study Suggests

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The development of a population of mutated blood cells — a phenomenon called clonal hematopoiesis of indeterminate potential — is more frequent in ANCA-associated vasculitis (AAV) patients than in healthy people, ... Read more

October 21, 2019October 22, 2019

Young Musician’s ‘Violin for Vasculitis’ Charity Strikes a Chord with Fellow Patients

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Allison Lint Ross looked like a typical healthy 16-year-old when she suddenly began to experience breathing difficulties, weakness, and disorientation that landed her in the emergency room. The talented ... Read more

October 17, 2019October 25, 2019

AAV Linked to Bleeding and Iron Deposits in Lungs in Case Study

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ANCA-associated vasculitis (AAV) can cause recurrent bleeding in the lungs, which manifest as hemosiderosis — an excessive accumulation of iron deposits in tissues — and lung nodules, a case ... Read more

October 16, 2019

Repeated Doses of Rituximab May Improve AAV Patients’ Response to the Medication, Study Suggests

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Administering rituximab repeatedly may improve the response of patients with ANCA-associated vasculitis (AAV) to the medication, a study says. The findings were reported in the study, “Non‐Linear Rituximab Pharmacokinetics ... Read more

October 10, 2019

Bacterial Infections, Especially in Lungs, Common in AAV Patients in Southern China, Study Reports

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Infection is a common complication of ANCA-associated vasculitis (AAV) that tends to develop within six months of diagnosis, and in cases of “mixed” infections — those caused by more ... Read more

October 8, 2019

Childhood Onset AAV Affects Multiple Organs at Diagnosis, May Be Managed with Rituximab, Study Suggests

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ANCA-associated vasculitis (AAV) with childhood onset often affects multiple organs, showing symptoms at diagnosis in the ear, nose, and throat, as well as pulmonary and renal complications, a single-center ... Read more

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